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Nr5a1 recombinant protein :: Steroidogenic factor 1 (Nr5a1) Recombinant Protein

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Catalog # MBS965782
Unit / Price
  0.05 mg (E-Coli)  /  $880 +1 FREE 8GB USB
  0.05 mg (Baculovirus)  /  $1,100 +1 FREE 8GB USB
  0.2 mg (E-Coli)  /  $1,180 +1 FREE 8GB USB
  0.5 mg (E-Coli)  /  $1,300 +1 FREE 8GB USB
  0.2 mg (Yeast)  /  $1,305 +1 FREE 8GB USB
  0.05 mg (Mammalian-Cell)  /  $1,345 +1 FREE 8GB USB
  0.1 mg (Baculovirus)  /  $1,395 +1 FREE 8GB USB
  0.5 mg (Yeast)  /  $1,480 +1 FREE 8GB USB
  1 mg (E-Coli)  /  $1,850 +2 FREE 8GB USB
  0.5 mg (Baculovirus)  /  $1,995 +2 FREE 8GB USB
  0.1 mg (Mammalian-Cell)  /  $2,035 +2 FREE 8GB USB
  1 mg (Yeast)  /  $2,250 +2 FREE 8GB USB
  1 mg (Baculovirus)  /  $2,630 +3 FREE 8GB USB
Nr5a1 recombinant protein
Product Name

Steroidogenic factor 1 (Nr5a1), Recombinant Protein

Also Known As

Recombinant Rat Steroidogenic factor 1 (Nr5a1)

Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
1-462aa, Full length protein
Sequence Length
462
Sequence
MDYSYDEDLD ELCPVCGDKV SGYHYGLLTC ESCKGFFKRT VQNNKHYTCT ESQSCKIDKT QRKRCPFCRF QKCLTVGMRL EAVRADRMRG GRNKFGPMYK RDRALKQQKK AQIRANGFKL ETGPPMGVPP PPPPPPDYML PPSLHAPEPK ALVSGPPSGP LGDFGAPSLP MAVPGPHGPL AGYLYPAFSN RTIKSEYPEP YASPPQQPGP PYSYPEPFSG GPNVPELILQ LLQLEPEEDQ VRARIVGCLQ EPAKSRPDQP APFSLLCRMA DQTFISIVDW ARRCMVFKEL EVADQMTLLQ NCWSELLVLD HIYRQVQYGK EDSILLVTGQ EVELSTVAVQ AGSLLHSLVL RAQELVLQLH ALQLDRQEFV CLKFLILFSL DVKFLNNHSL VKDAQEKANA ALLDYTLCHY PHCGDKFQQL LLCLVEVRAL SMQAKEYLYH KHLGNEMPRN NLLIEMLQAK QT
3D Structure
ModBase 3D Structure for P50569
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Species
Rat
Storage Buffer
Tris-based buffer, 50% glycerol
Tag Information
Tag type will be determined during the manufacturing process
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of Nr5a1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
Nr5a1 recombinant protein
This protein is a transcriptional activator involved in sex determination. The encoded protein binds DNA as a monomer. Defects in this gene are a cause of XY sex reversal with or without adrenal failure as well as adrenocortical insufficiency without ovarian defect.
NCBI/Uniprot data below describe general gene information for Nr5a1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Related Accession #
Molecular Weight
52,087 Da
NCBI Official Full Name
steroidogenic factor 1
NCBI Official Synonym Full Names
nuclear receptor subfamily 5, group A, member 1
NCBI Official Symbol
Nr5a1  [Similar Products]
NCBI Official Synonym Symbols
Sf-1; Ad4bp; Ftzf1; Ad4BP/SF-1
  [Similar Products]
NCBI Protein Information
steroidogenic factor 1
UniProt Protein Name
Steroidogenic factor 1
UniProt Synonym Protein Names
Adrenal 4-binding protein; Fushi tarazu factor homolog 1; Nuclear receptor subfamily 5 group A member 1; Steroid hormone receptor Ad4BP
Protein Family
UniProt Gene Name
Nr5a1  [Similar Products]
UniProt Synonym Gene Names
Ftzf1; SF-1; STF-1  [Similar Products]
NCBI Summary for Nr5a1
transcription factor; essential for adrenal and gonadal development [RGD, Feb 2006]
UniProt Comments for Nr5a1
Transcriptional activator. Seems to be essential for sexual differentiation and formation of the primary steroidogenic tissues. Binds to the Ad4 site found in the promoter region of steroidogenic P450 genes such as CYP11A, CYP11B and CYP21B. Also regulates the AMH/Muellerian inhibiting substance gene as well as the AHCH and STAR genes. 5'-YCAAGGYC-3' and 5'-RRAGGTCA-3' are the consensus sequences for the recognition by NR5A1. The SFPQ-NONO-NR5A1 complex binds to the CYP17 promoter and regulates basal and cAMP-dependent transcriptional activity. Binds phosphatidylcholine and phospholipids with a phosphatidylinositol (PI) headgroup, in particular PI(3,4)P2 and PI(3,4,5)P3. Activated by the phosphorylation of NR5A1 by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation ().
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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