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NRG4 cdna clone

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Catalog # MBS1277135
Unit / Price
  0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $165 +1 FREE 8GB USB
NRG4 cdna clone
Product Name

NRG4, cDNA Clone

Popular Item
Full Product Name

NRG4 cDNA Clone

Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
atgccaacag atcacgaaga gccctgtggt cccagtcaca agtcgttttg cctgaatggg gggctttgtt atgtgatacc tactattccc agcccatttt gtaggtgcgt tgaaaactat acaggagctc gttgtgaaga ggtttttctc ccaggctcca gcatccaaac taaaagtaac ctgtttgaag cttttgtggc attggcggtc ctagtaacac ttatcattgg agccttctac ttcctttgca ggaaaggcca ctttcagaga gccagttcag tccagtatga tatcaacctg gtagagacga gcagtaccag tgcccaccac agtcatgaac aacactga
OMIM
610894
Vector
pENTR223.1
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of NRG4 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for NRG4. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
12,722 Da
NCBI Official Full Name
Homo sapiens neuregulin 4, mRNA
NCBI Official Synonym Full Names
neuregulin 4
NCBI Official Symbol
NCBI Official Synonym Symbols
NCBI Protein Information
pro-neuregulin-4, membrane-bound isoform
UniProt Protein Name
Pro-neuregulin-4, membrane-bound isoform
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
Pro-NRG4; NRG-4  [Similar Products]
UniProt Entry Name
NRG4_HUMAN
NCBI Summary for NRG4
The neuregulins, including NRG4, activate type-1 growth factor receptors (see EGFR; MIM 131550) to initiating cell-to-cell signaling through tyrosine phosphorylation (Harari et al., 1999 [PubMed 10348342]).[supplied by OMIM, Mar 2008]
UniProt Comments for NRG4
NRG4: Low affinity ligand for the ERBB4 tyrosine kinase receptor. Concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. Does not bind to the ERBB1, ERBB2 and ERBB3 receptors. Belongs to the neuregulin family.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 15q24.2

Cellular Component: extracellular region; extracellular space

Molecular Function: phosphatidylinositol-4,5-bisphosphate 3-kinase activity; protein binding; protein-tyrosine kinase activity; Ras guanyl-nucleotide exchange factor activity; receptor binding

Biological Process: MAPKKK cascade; organ development; phosphoinositide-mediated signaling; regulation of phosphoinositide 3-kinase cascade
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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