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NRP2 cdna clone

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Catalog # MBS1272415
Unit / Price
  0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $165 +1 FREE 8GB USB
NRP2 cdna clone
Product Name

NRP2, cDNA Clone

Popular Item
Full Product Name

NRP2 cDNA Clone

Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
atggatatgt ttcctctcac ctgggttttc ttagccctct acttttcaag acaccaagtg agaggccaac cagacccacc gtgcggaggt cgtttgaatt ccaaagatgc tggctatatc acctctcccg gttaccccca ggactacccc tcccaccaga actgcgagtg gattgtttac gcccccgaac ccaaccagaa gattgtcctc aacttcaacc ctcactttga aatcgagaag cacgactgca acttgctgtc tgcttggaaa atttcactca caagccgcag ctttgcctga
OMIM
602070
Vector
pENTR223.1
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of NRP2 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for NRP2. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
62,458 Da
NCBI Official Full Name
Homo sapiens neuropilin 2, mRNA
NCBI Official Synonym Full Names
neuropilin 2
NCBI Official Symbol
NCBI Official Synonym Symbols
NP2; NPN2; PRO2714; VEGF165R2
  [Similar Products]
NCBI Protein Information
neuropilin-2
UniProt Protein Name
Neuropilin-2
UniProt Synonym Protein Names
Vascular endothelial cell growth factor 165 receptor 2
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
VEGF165R2  [Similar Products]
UniProt Entry Name
NRP2_HUMAN
NCBI Summary for NRP2
This gene encodes a member of the neuropilin family of receptor proteins. The encoded transmembrane protein binds to SEMA3C protein {sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C} and SEMA3F protein {sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F}, and interacts with vascular endothelial growth factor (VEGF). This protein may play a role in cardiovascular development, axon guidance, and tumorigenesis. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
UniProt Comments for NRP2
NRP2: High affinity receptor for semaphorins 3C, 3F, VEGF-165 and VEGF-145 isoforms of VEGF, and the PLGF-2 isoform of PGF. Heterodimer with NRP1. Binds PLXNB1. Belongs to the neuropilin family. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Motility/polarity/chemotaxis; Membrane protein, integral; Receptor, misc.

Chromosomal Location of Human Ortholog: 2q33.3

Cellular Component: membrane; plasma membrane

Molecular Function: growth factor binding; receptor activity

Biological Process: axon extension involved in axon guidance; nerve development; positive regulation of endothelial cell proliferation; vascular endothelial growth factor receptor signaling pathway
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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