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NXF1 cdna clone

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Catalog # MBS1274751
Unit / Price
  0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $285 +1 FREE 8GB USB
NXF1 cdna clone
Product Name

NXF1, cDNA Clone

Popular Item
Also Known As

NXF1 cDNA Clone

Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Length
atggcggacg aggggaagtc gtacagcgaa cacgatgatg aacgcgttaa tttccctcaa agaaagaaga aaggccgggg tcccttccgg tggaaatatg gtgaaggaaa ccgtaggtct ggaagaggcg gttctggtat tcggtcttcc cgccttgagg aagatgatgg agatgtggca atgagtgatg cccaggatgg tccccgagta cgatacaacc cctataccac ccgacctaac cgtcggggtg atacttggca tgatcgagat cgcattcatg ttactgtgcg gagagacaga gctcctccag agagaggagg ggctggcacc agccaggatg ggacctcaaa gaactggttc aagattacaa ttccttatgg cagaaagtat gacaaggcat ggctcctgag catgattcag agcaagtgca gtgtgccctt cacccctatt gagtttcact atgagaatac acgggcccag ttcttcgttg aagacgccag tactgcctct gcattgaagg ctgtcaacta taagattttg gatcgggaga accgaaggat atctatcatc atcaactctt ctgctccacc ccacactata ctgaatgaac tgaagccaga acaagtagaa cagctaaagc tgatcatgag caaacgatac gatggctccc aacaagccct tgacctcaaa ggcctccgtt cagacccaga tttggtggcc cagaacattg acgttgtcct gaatcgcaga agctgtatgg cagctaccct gaggatcatt gaagagaaca tccctgagct attgtccttg aacttgagca acaacaggct gtacaggctg gatgacatgt ctagcattgt tcagaaggca cccaacctga agatcctaaa cctttctgga aatgaattga agtctgagcg ggaattggac aagataaagg ggctgaagct agaagagctc tggctcgatg gaaactccct gtgtgacacc ttccgagacc agtccaccta catcagcgcc attcgcgaac gatttcccaa gttactacgc ctggatggcc atgagctacc cccaccaatt gcctttgatg ttgaagcccc cacgacgtta ccgccctgca agggaagcta ttttggaaca gaaaacttga agagtctggt cttgcacttc ctgcaacagt actatgcaat ttacgactct ggagaccgac aagggctcct ggatgcctac catgatgggg cctgctgttc cctgagcatt cctttcattc ctcagaaccc tgcccgaagc agcttagccg agtatttcaa ggatagcaga aatgtgaaga agcttaaaga ccctaccttg cggttccggc tgctgaagca cacgcgtctc aacgttgttg ccttcctcaa tgagttgccc aaaacccagc acgacgtcaa ttccttcgtg gtagacataa gcgcccagac aagcacattg ctgtgttttt ctgtcaatgg agtcttcaag gaagtggacg gaaagtcccg ggattctttg cgagccttca cccggacatt cattgctgtt cctgctagca attcagggct atgtattgta aatgatgagc tatttgtgcg gaatgccagt tctgaagaga tccaaagagc cttcgctatg cctgcaccca cgccttcctc cagcccggtg cccaccctct ctccagagca gcaggaaatg ttgcaagcat tctctaccca gtctggcatg aacctcgagt ggtcccagaa gtgccttcag gacaacaact gggactacac cagatctgcc caggccttca ctcatctcaa ggccaagggc gagatcccag aagtggcatt catgaagtga
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of NXF1 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for NXF1. It may not necessarily be applicable to this product.
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
40,476 Da
NCBI Official Full Name
Homo sapiens nuclear RNA export factor 1, mRNA
NCBI Official Synonym Full Names
nuclear RNA export factor 1
NCBI Official Symbol
NCBI Official Synonym Symbols
  [Similar Products]
NCBI Protein Information
nuclear RNA export factor 1
UniProt Protein Name
Nuclear RNA export factor 1
UniProt Synonym Protein Names
Tip-associated protein; Tip-associating protein; mRNA export factor TAP
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
UniProt Entry Name
NCBI Summary for NXF1
This gene is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. Alternative splicing seems to be a common mechanism in this gene family. The encoded protein of this gene shuttles between the nucleus and the cytoplasm and binds in vivo to poly(A)+ RNA. It is the vertebrate homologue of the yeast protein Mex67p. The encoded protein overcomes the mRNA export block caused by the presence of saturating amounts of CTE (constitutive transport element) RNA of type D retroviruses. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]
UniProt Comments for NXF1
NXF1: Involved in the nuclear export of mRNA species bearing retroviral constitutive transport elements (CTE) and in the export of mRNA from the nucleus to the cytoplasm. The NXF1-NXT1 heterodimer is involved in the export of HSP70 mRNA in conjunction with ALYREF/THOC4 and THOC5. Belongs to the NXF family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: RNA-binding

Chromosomal Location of Human Ortholog: 11q12-q13

Cellular Component: cytosol; nuclear speck; nucleoplasm; nucleus

Molecular Function: protein binding; single-stranded RNA binding

Biological Process: mRNA export from nucleus; poly(A)+ mRNA export from nucleus; RNA export from nucleus
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While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

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