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OGDH elisa kit :: Rat 2-oxoglutae dehydrogenase, mitochondrial (OGDH) ELISA Kit

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Catalog # MBS7210619
Unit / Price
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OGDH elisa kit
Product Name

2-oxoglutae dehydrogenase, mitochondrial (OGDH), ELISA Kit

Full Product Name

Rat 2-oxoglutae dehydrogenase, mitochondrial (OGDH) ELISA Kit

Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Request for Current Manual Insert
Species Reactivity
Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate
Assay Type
Detection Range
Preparation and Storage
Store all reagents at 2-8 degree C.
Sample Preparation
We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact our technical support team
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
Other Notes
Small volumes of OGDH elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for OGDHpurchase
MBS7210619 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the 2-oxoglutae dehydrogenase, mitochondrial (OGDH) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing OGDH. The ELISA analytical biochemical technique of the MBS7210619 kit is based on OGDH antibody-OGDH antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect OGDH antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, OGDH. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
Product Categories/Family for OGDH elisa kit
NCBI/Uniprot data below describe general gene information for OGDH. It may not necessarily be applicable to this product.
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
48,180 Da
NCBI Official Full Name
2-oxoglutarate dehydrogenase, mitochondrial isoform 2
NCBI Official Synonym Full Names
oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
NCBI Official Symbol
NCBI Official Synonym Symbols
  [Similar Products]
NCBI Protein Information
2-oxoglutarate dehydrogenase, mitochondrial; OGDC-E1; oxoglutarate decarboxylase; 2-oxoglutarate dehydrogenase complex component E1; oxoglutarate dehydrogenase (succinyl-transferring)
UniProt Protein Name
2-oxoglutarate dehydrogenase, mitochondrial
UniProt Synonym Protein Names
2-oxoglutarate dehydrogenase complex component E1; OGDC-E1; Alpha-ketoglutarate dehydrogenase
UniProt Gene Name
UniProt Synonym Gene Names
OGDC-E1  [Similar Products]
UniProt Entry Name
NCBI Summary for OGDH
This gene encodes one subunit of the 2-oxoglutarate dehydrogenase complex. This complex catalyzes the overall conversion of 2-oxoglutarate (alpha-ketoglutarate) to succinyl-CoA and CO(2) during the Krebs cycle. The protein is located in the mitochondrial matrix and uses thiamine pyrophosphate as a cofactor. A congenital deficiency in 2-oxoglutarate dehydrogenase activity is believed to lead to hypotonia, metabolic acidosis, and hyperlactatemia. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Sep 2009]
UniProt Comments for OGDH
OGDH: The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components: 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3). Belongs to the alpha-ketoglutarate dehydrogenase family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: EC; Carbohydrate Metabolism - citrate (TCA) cycle; Amino Acid Metabolism - tryptophan; Oxidoreductase; Amino Acid Metabolism - lysine degradation; Mitochondrial

Chromosomal Location of Human Ortholog: 7p14-p13

Cellular Component: mitochondrion; mitochondrial matrix; mitochondrial membrane; cytosol; oxoglutarate dehydrogenase complex

Molecular Function: metal ion binding; heat shock protein binding; chaperone binding; thiamin pyrophosphate binding; oxoglutarate dehydrogenase (succinyl-transferring) activity

Biological Process: generation of precursor metabolites and energy; glycolysis; striatum development; tricarboxylic acid cycle; succinyl-CoA metabolic process; hippocampus development; pyramidal neuron development; thalamus development; 2-oxoglutarate metabolic process; cerebellar cortex development; cellular metabolic process; tangential migration from the subventricular zone to the olfactory bulb; NADH metabolic process; lysine catabolic process

Disease: Alpha-ketoglutarate Dehydrogenase Deficiency
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While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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