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OGG1 peptide

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Catalog # MBS426568
Unit / Price
  0.1 mg  /  $190 +1 FREE 8GB USB
OGG1 peptide
Product Name

Ogg1, Peptide

Also Known As

Ogg1 Immunizing Peptide

Product Synonym Names
Ogg1; 8-oxoguanine DNA glycosylase; Mmh; Ogg1 (mouse)
Product Gene Name
Antibody/Peptide Pairs
Ogg1 peptide (MBS426568) is used for blocking the activity of Ogg1 antibody (MBS420013)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Length
345
Sequence
C-HPKTSQAK GPSPLANK
Species Reactivity
Mouse, Rat
Form/Format
100ug of dried peptide
Preparation and Storage
Shipped at ambient temperature, store at -20 degree C
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Other Notes
Small volumes of OGG1 peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for OGG1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
38,883 Da
NCBI Official Full Name
8-oxoguanine DNA-glycosylase 1
NCBI Official Synonym Full Names
8-oxoguanine DNA-glycosylase 1
NCBI Official Symbol
NCBI Official Synonym Symbols
NCBI Protein Information
N-glycosylase/DNA lyase
UniProt Protein Name
N-glycosylase/DNA lyase
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
AP lyase  [Similar Products]
UniProt Entry Name
OGG1_MOUSE
UniProt Comments for OGG1
OGG1: DNA repair enzyme that incises DNA at 8-oxoG residues. Excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N- methylformamidopyrimidine (FAPY) from damaged DNA. Has a beta- lyase activity that nicks DNA 3' to the lesion. Defects in OGG1 may be a cause of renal cell carcinoma (RCC). It is a heterogeneous group of sporadic or hereditary carcinoma derived from cells of the proximal renal tubular epithelium. It is subclassified into clear cell renal carcinoma (non-papillary carcinoma), papillary renal cell carcinoma, chromophobe renal cell carcinoma, collecting duct carcinoma with medullary carcinoma of the kidney, and unclassified renal cell carcinoma. Belongs to the type-1 OGG1 family. 8 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 4.2.99.18; DNA repair, damage; Deoxyribonuclease; Lyase

Cellular Component: mitochondrion; nuclear matrix; nuclear speck; nucleoplasm; nucleus; protein complex

Molecular Function: 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity; catalytic activity; damaged DNA binding; DNA binding; DNA N-glycosylase activity; DNA-(apurinic or apyrimidinic site) lyase activity; DNA-3-methyladenine glycosylase III activity; hydrolase activity; hydrolase activity, acting on glycosyl bonds; lyase activity; microtubule binding; oxidized base lesion DNA N-glycosylase activity; oxidized purine base lesion DNA N-glycosylase activity; oxidized purine DNA binding; purine-specific mismatch base pair DNA N-glycosylase activity; single-strand selective uracil DNA N-glycosylase activity; uracil DNA N-glycosylase activity

Biological Process: aging; base-excision repair; DNA repair; metabolic process; negative regulation of apoptosis; nucleotide-excision repair; nucleotide-excision repair, DNA incision; regulation of protein import into nucleus, translocation; regulation of transcription, DNA-dependent; response to DNA damage stimulus; response to estradiol stimulus; response to oxidative stress; response to radiation
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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