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Omega-HXTX-Hv1a recombinant protein :: Omega-hexatoxin-Hv1a Recombinant Protein

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Catalog # MBS1073255
Unit / Price
  0.01 mg (E-Coli)  /  $110 +1 FREE 8GB USB
  0.05 mg (E-Coli)  /  $190 +1 FREE 8GB USB
  0.1 mg (E-Coli)  /  $285 +1 FREE 8GB USB
  0.2 mg (E-Coli)  /  $460 +1 FREE 8GB USB
  0.05 mg (Yeast)  /  $610 +1 FREE 8GB USB
  0.5 mg (E-Coli)  /  $750 +1 FREE 8GB USB
  0.05 mg (Baculovirus)  /  $770 +1 FREE 8GB USB
  0.2 mg (Yeast)  /  $825 +1 FREE 8GB USB
  0.5 mg (Yeast)  /  $930 +1 FREE 8GB USB
  0.1 mg (Baculovirus)  /  $975 +1 FREE 8GB USB
  0.05 mg (Mammalian-Cell)  /  $1,010 +1 FREE 8GB USB
  1 mg (E-Coli)  /  $1,180 +1 FREE 8GB USB
  1 mg (Yeast)  /  $1,400 +1 FREE 8GB USB
  0.5 mg (Baculovirus)  /  $1,410 +1 FREE 8GB USB
  0.1 mg (Mammalian-Cell)  /  $1,545 +1 FREE 8GB USB
  1 mg (Baculovirus)  /  $1,900 +2 FREE 8GB USB
SDS-PAGE
Product Name

Omega-hexatoxin-Hv1a (Omega-HXTX-Hv1a), Recombinant Protein

Popular Item
Also Known As

Recombinant Hadronyche versuta (Blue mountains funnel-web spider) (Atrax versutus) Omega-hexatoxin-Hv1a

Product Synonym Names
Omega-atracotoxin-Hv1a; AcTx-Hv1; Omega-AcTx-Hv1a
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
1-37aa; Full Length
Sequence Length
37
Sequence
SPTCIPSGQP CPYNENCCSQ SCTFKENENG NTVKRCD
3D Structure
ModBase 3D Structure for P56207
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater than 90% as determined by SDS-PAGE. (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Species
Hadronyche versuta (Blue mountains funnel-web spider) (Atrax versutus)
Preparation and Storage
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of Omega-HXTX-Hv1a recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
Omega-HXTX-Hv1a recombinant protein
Reversibly and voltage-independently blocks both mid-low- (M-LVA) and high-voltage-activated (HVA) calcium channels in cockroach DUM neurons. Lethal to many insect orders but not toxic to mice or rabbits. May target the insect high-voltage-activated calcium channel Dmca1D. Also inhibits acarines calcium channels. An extremely high toxin concentration partially inhibits Cav1. 2/CACNA1C, Cav2. 1/CACNA1A and Cav2. 2/CACNA1B calcium channel of rats. As for omega-AcTx-Hv2a, the phenotypic effect of injection of this toxin into lone star ticks (Amblyomma americanum) is curling of all eight legs into closed loops.

Omega-HXTX-Hv1a recombinant protein SDS-PAGE image
(Note: Representative image, actual molecular weight may vary depending on Tag type and expression host)
NCBI/Uniprot data below describe general gene information for Omega-HXTX-Hv1a. It may not necessarily be applicable to this product.
NCBI GI #
NCBI Accession #
UniProt Primary Accession #
Molecular Weight
NCBI Official Full Name
Omega-hexatoxin-Hv1a
UniProt Protein Name
Omega-hexatoxin-Hv1a
UniProt Synonym Protein Names
Omega-atracotoxin-Hv1a; AcTx-Hv1; Omega-AcTx-Hv1a
Protein Family
UniProt Gene Name
Omega-HXTX-Hv1a  [Similar Products]
UniProt Synonym Gene Names
AcTx-Hv1; Omega-AcTx-Hv1a  [Similar Products]
UniProt Entry Name
TO1A_HADVE
UniProt Comments for Omega-HXTX-Hv1a
Reversibly and voltage-independently blocks both mid-low- (M-LVA) and high-voltage-activated (HVA) calcium channels in cockroach DUM neurons. Lethal to many insect orders but not toxic to mice or rabbits. May target the insect high-voltage-activated calcium channel Dmca1D. Also inhibits acarines calcium channels. An extremely high toxin concentration partially inhibits Cav1.2/CACNA1C, Cav2.1/CACNA1A and Cav2.2/CACNA1B calcium channel of rats. As for omega-AcTx-Hv2a, the phenotypic effect of injection of this toxin into lone star ticks (Amblyomma americanum) is curling of all eight legs into closed loops.
Product References and Citations for Omega-HXTX-Hv1a recombinant protein
"The structure of a novel insecticidal neurotoxin, omega-atracotoxin-HV1, from the venom of an Australian funnel web spider." Fletcher J.I., Smith R., O'Donoghue S.I., Nilges M., Connor M., Howden M.E.H., Christie M.J., King G.F. Nat. Struct. Biol. 4:559-566(1997)

Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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