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ORF3 recombinant protein :: Hepatitis E virus genotype 1 Protein ORF3 Recombinant Protein

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Catalog # MBS1004157
Unit / Price
  0.01 mg (E-Coli)  /  $110 +1 FREE 8GB USB
  0.05 mg (E-Coli)  /  $190 +1 FREE 8GB USB
  0.1 mg (E-Coli)  /  $285 +1 FREE 8GB USB
  0.2 mg (E-Coli)  /  $460 +1 FREE 8GB USB
  0.05 mg (Yeast)  /  $675 +1 FREE 8GB USB
  0.5 mg (E-Coli)  /  $750 +1 FREE 8GB USB
  0.05 mg (Baculovirus)  /  $830 +1 FREE 8GB USB
  0.2 mg (Yeast)  /  $915 +1 FREE 8GB USB
  0.5 mg (Yeast)  /  $1,025 +1 FREE 8GB USB
  0.1 mg (Baculovirus)  /  $1,045 +1 FREE 8GB USB
  0.05 mg (Mammalian-Cell)  /  $1,070 +1 FREE 8GB USB
  1 mg (E-Coli)  /  $1,180 +1 FREE 8GB USB
  0.5 mg (Baculovirus)  /  $1,515 +1 FREE 8GB USB
  1 mg (Yeast)  /  $1,555 +1 FREE 8GB USB
  0.1 mg (Mammalian-Cell)  /  $1,635 +2 FREE 8GB USB
  1 mg (Baculovirus)  /  $2,035 +2 FREE 8GB USB
SDS-Page
Product Name

Hepatitis E virus genotype 1 Protein ORF3, Recombinant Protein

Popular Item
Also Known As

Recombinant Hepatitis E virus genotype 1 Protein ORF3

Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
1-114aa; Full Length
Sequence Length
114
Sequence
MGSRPWALGL FCCCSSCFCL CCSRHRPVSR LAAVVGGAAA VPAVVSGVTG LILSPSQSPI FIQPTPSPRM SPLRPGLDLV FANPSDHSAP LGATRPSAPP LPHVVDLPQL GPRR
3D Structure
ModBase 3D Structure for O90299
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater than 90% as determined by SDS-PAGE. (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Preparation and Storage
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of ORF3 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
ORF3 recombinant protein
May act as a viral regulatory protein involved in the modulation of mitogenic signaling pathways. May be involved in virion morphogenesis and viral pathogenesis. Expedites the processing and secretion of AMBP from the hepatocyte.

ORF3 recombinant protein SDS-Page image
(Note: Representative image, actual molecular weight may vary depending on Tag type and expression host)
NCBI/Uniprot data below describe general gene information for ORF3. It may not necessarily be applicable to this product.
NCBI GI #
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
Molecular Weight
27.8kD
NCBI Official Full Name
Protein ORF3
UniProt Protein Name
Protein ORF3
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
pORF3  [Similar Products]
UniProt Entry Name
ORF3_HEVHY
UniProt Comments for ORF3
May act as a viral regulatory protein involved in the modulation of mitogenic signaling pathways. May be involved in virion morphogenesis and viral pathogenesis. Expedites the processing and secretion of AMBP from the hepatocyte.
Product References and Citations for ORF3 recombinant protein
An Indian strain of hepatitis E virus (HEV) cloning, sequence, and expression of structural region and antibody responses in sera from individuals from an area of high-level HEV endemicity.Panda S.K., Nanda S.K., Zafrullah M., Ansari I.H., Ozdener M.H., Jameel S.J. Clin. Microbiol. 33:2653-2659(1995) The in vitro-synthesized RNA from a cDNA clone of hepatitis E virus is infectious.Panda S.K., Ansari I.H., Durgapal H., Agrawal S., Jameel S.J. Virol. 74:2430-2437(2000) The ORF3 protein of hepatitis E virus is a phosphoprotein that associates with the cytoskeleton.Zafrullah M., Ozdener M.H., Panda S.K., Jameel S.J. Virol. 71:9045-9053(1997) The ORF3 protein of hepatitis E virus binds to Src homology 3 domains and activates MAPK.Korkaya H., Jameel S., Gupta D., Tyagi S., Kumar R., Zafrullah M., Mazumdar M., Lal S.K., Xiaofang L., Sehgal D., Das S.R., Sahal D.J. Biol. Chem. 276:42389-42400(2001) Self-association and mapping of the interaction domain of hepatitis E virus ORF3 protein.Tyagi S., Jameel S., Lal S.K.J. Virol. 75:2493-2498(2001) The phosphorylated form of the ORF3 protein of hepatitis E virus interacts with its non-glycosylated form of the major capsid protein, ORF2.Tyagi S., Korkaya H., Zafrullah M., Jameel S., Lal S.K.J. Biol. Chem. 277:22759-22767(2002) The ORF3 protein of hepatitis E virus interacts with liver-specific alpha1-microglobulin and its precursor alpha1-microglobulin/bikunin precursor (AMBP) and expedites their export from the hepatocyte.Tyagi S., Surjit M., Roy A.K., Jameel S., Lal S.K.J. Biol. Chem. 279:29308-29319(2004) The 41-amino-acid C-terminal region of the hepatitis E virus ORF3 protein interacts with bikunin, a Kunitz-type serine protease inhibitor.Tyagi S., Surjit M., Lal S.K.J. Virol. 79:12081-12087(2005) The ORF3 protein of hepatitis E virus interacts with hemopexin by means of its 26 amino acid N-terminal hydrophobic domain II.Ratra R., Kar-Roy A., Lal S.K.Biochemistry 47:1957-1969(2008)

Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

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