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OSCAR elisa kit :: Human osteoclast associated, immunoglobulin-like receptor ELISA Kit

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Catalog # MBS946901
Unit / Price
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  24-Strip-Wells (LIMIT 1)  /  $240 +1 FREE 8GB USB
  48-Strip-Wells  /  $435 +1 FREE 8GB USB
  96-Strip-Wells  /  $625 +1 FREE 8GB USB
  5x96-Strip-Wells  /  $2,595 +3 FREE 8GB USB
  10x96-Strip-Wells  /  $4,905 +6 FREE 8GB USB
Typical Testing Data/Standard Curve (for reference only)
Product Name

osteoclast associated, immunoglobulin-like receptor (OSCAR), ELISA Kit

Popular Item
Full Product Name

Human Osteoclast-associated immunoglobulin-like receptor, OSCAR ELISA Kit

Product Synonym Names
Human Osteoclast-associated immunoglobulin-like receptor (OSCAR) ELISA kit; MGC33613; PIGR3; osteoclast associated receptor OSCAR-S1; osteoclast associated receptor OSCAR-S2; osteoclast-associated receptor; polymeric immunoglobulin receptor 3; osteoclast associated; immunoglobulin-like receptor
Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Request for Current Manual Insert
MBS946901 Testing Data
OMIM
606862
3D Structure
ModBase 3D Structure for Q8IYS5
Species Reactivity
Specificity
This assay has high sensitivity and excellent specificity for detection of human OSCAR. No significant cross-reactivity or interference between human OSCAR and analogues was observed.
Samples
Serum, plasma, tissue homogenates
Assay Type
Sandwich
Detection Range
6.25 ng/ml - 400 ng/ml.
Sensitivity
The minimum detectable dose of human OSCAR is typically less than 1.56 ng/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations.
Intra-assay Precision
Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess.
Inter-assay Precision
Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.
Preparation and Storage
Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Product Note
Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
Other Notes
Small volumes of OSCAR elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for OSCARpurchase
MBS946901 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the osteoclast associated, immunoglobulin-like receptor (OSCAR) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing OSCAR. The ELISA analytical biochemical technique of the MBS946901 kit is based on OSCAR antibody-OSCAR antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect OSCAR antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, OSCAR. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
Related Product Information for
OSCAR elisa kit
Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for OSCAR has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any OSCAR present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for OSCAR is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of OSCAR bound in the initial step. The color development is stopped and the intensity of the color is measured.

Typical Testing Data/Standard Curve (for reference only) of OSCAR elisa kit
OSCAR elisa kit Typical Testing Data/Standard Curve (for reference only) image
Sample Manual Insert of MBS946901. Click to request current manual
NCBI/Uniprot data below describe general gene information for OSCAR. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
30,481 Da
NCBI Official Full Name
osteoclast-associated immunoglobulin-like receptor isoform 6
NCBI Official Synonym Full Names
osteoclast associated, immunoglobulin-like receptor
NCBI Official Symbol
OSCAR  [Similar Products]
NCBI Official Synonym Symbols
PIGR3; PIgR-3
  [Similar Products]
NCBI Protein Information
osteoclast-associated immunoglobulin-like receptor; poly-Ig receptor 3; polymeric immunoglobulin receptor 3; osteoclast associated receptor OSCAR-S1; osteoclast associated receptor OSCAR-S2
UniProt Protein Name
Osteoclast-associated immunoglobulin-like receptor
UniProt Synonym Protein Names
Polymeric immunoglobulin receptor 3; PIgR-3; PIgR3; Poly-Ig receptor 3
UniProt Gene Name
OSCAR  [Similar Products]
UniProt Synonym Gene Names
Osteoclast-associated receptor; hOSCAR; PIgR-3; PIgR3; Poly-Ig receptor 3  [Similar Products]
UniProt Entry Name
OSCAR_HUMAN
NCBI Summary for OSCAR
Osteoclasts are multinucleated cells that resorb bone and are essential for bone homeostasis. This gene encodes an osteoclast-associated receptor (OSCAR), which is a member of the leukocyte receptor complex protein family that plays critical roles in the regulation of both innate and adaptive immune responses. The encoded protein may play a role in oxidative stress-mediated atherogenesis as well as monocyte adhesion. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2013]
UniProt Comments for OSCAR
OSCAR: Regulator of osteoclastogenesis which plays an important bone-specific function in osteoclast differentiation. Belongs to the leukocyte receptor complex/polymeric immunogobulin receptor (PIR/LRC) family. 7 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Receptor, misc.

Chromosomal Location of Human Ortholog: 19q13.42

Cellular Component: plasma membrane; integral to membrane
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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