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PALLD peptide :: Palladin Peptide

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Catalog # MBS426674
Unit / Price
  0.1 mg  /  $190 +1 FREE 8GB USB
PALLD peptide
Product Name

Palladin (PALLD), Peptide

Full Product Name

Palladin Immunizing Peptide

Product Synonym Names
PALLD; palladin, cytoskeletal associated protein; CGI-151; FLJ22190; FLJ38193; FLJ39139; KIAA0992; PNCA1; SIH002; palladin; sarcoma antigen NY-SAR-77; Palladin; Palladin (aa895-907)
Product Gene Name
Antibody/Peptide Pairs
Palladin peptide (MBS426674) is used for blocking the activity of Palladin antibody (MBS421830)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
C-RDSGDENE PIQER
OMIM
606856
Species Reactivity
Human, Mouse, Rat, Dog
Form/Format
100ug of dried peptide
Preparation and Storage
Shipped at ambient temperature, store at -20 degree C
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Other Notes
Small volumes of PALLD peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for PALLD. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
123,693 Da
NCBI Official Full Name
palladin isoform 2
NCBI Official Synonym Full Names
palladin, cytoskeletal associated protein
NCBI Official Symbol
PALLD  [Similar Products]
NCBI Official Synonym Symbols
MYN; PNCA1; CGI151; SIH002; CGI-151
  [Similar Products]
NCBI Protein Information
palladin
UniProt Protein Name
Palladin
UniProt Synonym Protein Names
SIH002; Sarcoma antigen NY-SAR-77
Protein Family
UniProt Gene Name
PALLD  [Similar Products]
UniProt Synonym Gene Names
KIAA0992  [Similar Products]
UniProt Entry Name
PALLD_HUMAN
NCBI Summary for PALLD
This gene encodes a cytoskeletal protein that is required for organizing the actin cytoskeleton. The protein is a component of actin-containing microfilaments, and it is involved in the control of cell shape, adhesion, and contraction. Polymorphisms in this gene are associated with a susceptibility to pancreatic cancer type 1, and also with a risk for myocardial infarction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
UniProt Comments for PALLD
palladin: Cytoskeletal protein required for organization of normal actin cytoskeleton. Roles in establishing cell morphology, motility, cell adhesion and cell-extracellular matrix interactions in a variety of cell types. May function as a scaffolding molecule with the potential to influence both actin polymerization and the assembly of existing actin filaments into higher-order arrays. Binds to proteins that bind to either monomeric or filamentous actin. Localizes at sites where active actin remodeling takes place, such as lamellipodia and membrane ruffles. Different isoforms may have functional differences. Involved in the control of morphological and cytoskeletal changes associated with dendritic cell maturation. Involved in targeting ACTN to specific subcellular foci. Genetic variations in PALLD are associated with susceptibility to pancreatic cancer type 1 (PNCA1). Expression is increased early in the development of pancreatic cancer: in normal-appearing whole tissue immediately adjacent to cancer, in the pre-cancer, and in both the familial and sporadic forms of the cancer. Genetic variations in PALLD may be associated with myocardial infarction. Belongs to the myotilin/palladin family. 9 isoforms of the human protein are produced by alternative splicing.

Protein type: Motility/polarity/chemotaxis; Cytoskeletal

Chromosomal Location of Human Ortholog: 4q32.3

Cellular Component: actin cytoskeleton; actin filament; axon; cytoplasm; focal adhesion; growth cone; lamellipodium; mitochondrion; nucleus; plasma membrane; podosome; ruffle; Z disc

Molecular Function: actin binding; muscle alpha-actinin binding; protein binding

Biological Process: actin cytoskeleton organization and biogenesis; cell migration; cytoskeleton organization and biogenesis

Disease: Pancreatic Cancer, Susceptibility To, 1
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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