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PANX1 cdna clone

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Catalog # MBS1277298
Unit / Price
  0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $165 +1 FREE 8GB USB
PANX1 cdna clone
Product Name

PANX1, cDNA Clone

Popular Item
Also Known As

PANX1 cDNA Clone

Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Length
1281
Sequence
atggccatcg ctcacctggc cacggagtac gtgttctcgg atttcttgct gaaggagccc acggagccca agttcaaggg gctgcgactg gagctggctg tggacaagat ggtcacgtgc attgcggtgg ggctgcccct gctgctcatc tcgctggcct tcgcgcagga gatctcgatt ggtacacaga taagctgttt ctctccaagt tctttctcct ggcgtcaggc tgcctttgtg gattcatatt gctgggcggc tgttcagcag aagaactcac tgcagagcga gtctggaaac ctcccactgt ggctgcataa gtttttcccc tacatcctgc tgctctttgc gatcctcctg tacctgcccc cgctgttctg gcgtttcgca gctgctcctc atatttgctc agacttgaag tttatcatgg aagaacttga caaagtttac aaccgtgcaa ttaaggctgc aaagagtgcg cgtgaccttg acatgagaga tggagcctgc tcagttccag gtgttaccga gaacttaggg caaagtttgt gggaggtatc tgaaagccac ttcaagtacc caattgtgga gcagtacttg aagacaaaga aaaattctaa taatttaatc atcaagtaca ttagctgccg cctgctgaca ctcatcatta tactgttagc gtgtatctac ctgggctatt acttcagcct ctcctcactc tcagacgagt ttgtgtgcag catcaaatca gggatcctga gaaacgacag caccgtgccc gatcagtttc agtgcaaact cattgccgtg ggcatcttcc agttgctcag tgtcattaac cttgtggttt atgtcctgct ggctcccgtg gttgtctaca cgctgtttgt tccattccga cagaagacag atgttctcaa agtgtacgaa atcctcccca cttttgatgt tctgcatttc aaatctgaag ggtacaacga tttgagcctc tacaatctct tcttggagga aaatataagt gaggtcaagt catacaagtg tcttaaggta ctggagaata ttaagagcag tggtcagggg atcgacccaa tgctactcct gacaaacctt ggcatgatca agatggatgt tgttgatggc aaaactccca tgtctgcaga gatgagagag gagcagggga accagacggc agagctccaa ggtatgaaca tagacagtga aactaaagca aataatggag agaagaatgc ccgacagaga cttctggatt cttcttgctg a
OMIM
608420
Vector
pENTR223.1
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of PANX1 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for PANX1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
47,635 Da
NCBI Official Full Name
Homo sapiens pannexin 1, mRNA
NCBI Official Synonym Full Names
pannexin 1
NCBI Official Symbol
PANX1  [Similar Products]
NCBI Official Synonym Symbols
PX1; MRS1; UNQ2529
  [Similar Products]
NCBI Protein Information
pannexin-1
UniProt Protein Name
Pannexin-1
Protein Family
UniProt Gene Name
PANX1  [Similar Products]
UniProt Synonym Gene Names
UniProt Entry Name
PANX1_HUMAN
NCBI Summary for PANX1
The protein encoded by this gene belongs to the innexin family. Innexin family members are the structural components of gap junctions. This protein and pannexin 2 are abundantly expressed in central nerve system (CNS) and are coexpressed in various neuronal populations. Studies in Xenopus oocytes suggest that this protein alone and in combination with pannexin 2 may form cell type-specific gap junctions with distinct properties. [provided by RefSeq, Jul 2008]
UniProt Comments for PANX1
PANX1: Structural component of the gap junctions and the hemichannels. May play a role as a Ca(2+)-leak channel to regulate ER Ca(2+) homeostasis. Belongs to the pannexin family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Membrane protein, multi-pass; Cell adhesion

Chromosomal Location of Human Ortholog: 11q21

Cellular Component: endoplasmic reticulum; membrane; plasma membrane

Molecular Function: calcium channel activity; gap junction hemi-channel activity; leak channel activity; receptor binding

Biological Process: calcium ion transport; cation transport; cell-cell signaling; positive regulation of interleukin-1 beta secretion
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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