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PAPPA2 elisa kit :: Mouse Pappalysin 2 ELISA Kit

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Catalog # MBS044768
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  48-Strip-Wells  /  $470 +1 FREE 8GB USB
  96-Strip-Wells  /  $680 +1 FREE 8GB USB
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PAPPA2 elisa kit
Product Name

Pappalysin 2 (PAPPA2), ELISA Kit

Popular Item
Full Product Name

Mouse Pappalysin 2 ELISA Kit

Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Request for Current Manual Insert
Chromosome Location
Chromosome: 1; NC_000001.10 (176432307..176811972). Location: 1q23-q25
3D Structure
ModBase 3D Structure for Q9BXP8
Species Reactivity
Specificity
No significant cross-reactivity or interference between this analyte and analogues is observed.
Samples
undiluted original Mouse body fluids, tissue homogenates, secretions or feces samples
Assay Type
Quantitative Sandwich
Detection Range
0.25 ng/ml - 8 ng/mL
Sensitivity
0.1 ng/mL
Intra-assay Precision
Intra-assay CV (%) is less than 15%.
Inter-assay Precision
Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
Preparation and Storage
Store all reagents at 2-8 degree C
Product Note
Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
Other Notes
Small volumes of PAPPA2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for PAPPA2purchase
MBS044768 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Pappalysin 2 (PAPPA2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing PAPPA2. The ELISA analytical biochemical technique of the MBS044768 kit is based on PAPPA2 antibody-PAPPA2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect PAPPA2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, PAPPA2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
Related Product Information for
PAPPA2 elisa kit
Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of PAPPA2 (hereafter termed "analyte") in undiluted original Mouse body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
Sample Manual Insert of MBS044768. Click to request current manual
NCBI/Uniprot data below describe general gene information for PAPPA2. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
198,539 Da
NCBI Official Full Name
pappalysin-2 isoform 1
NCBI Official Synonym Full Names
pappalysin 2
NCBI Official Symbol
PAPPA2  [Similar Products]
NCBI Official Synonym Symbols
PAPPE; PLAC3; PAPP-E; PAPP-A2
  [Similar Products]
NCBI Protein Information
pappalysin-2; placenta-specific 3; pregnancy-associated plasma protein E1; pregnancy-associated plasma preproprotein-A2
UniProt Protein Name
Pappalysin-2
UniProt Synonym Protein Names
Pregnancy-associated plasma protein A2; PAPP-A2; Pregnancy-associated plasma protein E1
Protein Family
UniProt Gene Name
PAPPA2  [Similar Products]
UniProt Synonym Gene Names
PLAC3; PAPP-A2; PAPP-E  [Similar Products]
UniProt Entry Name
PAPP2_HUMAN
NCBI Summary for PAPPA2
This gene encodes a member of the pappalysin family of metzincin metalloproteinases. The encoded protein cleaves insulin-like growth factor-binding protein 5 and is thought to be a local regulator of insulin-like growth factor (IGF) bioavailability. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2010]
UniProt Comments for PAPPA2
PAPPA2: Metalloproteinase which specifically cleaves IGFBP-5. Shows limited proteolysis toward IGFBP-3. Belongs to the peptidase M43B family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted; Protease; Secreted, signal peptide; EC 3.4.24.-

Chromosomal Location of Human Ortholog: 1q25.2

Cellular Component: membrane; extracellular region; intracellular

Molecular Function: zinc ion binding; metallopeptidase activity

Biological Process: cellular protein metabolic process; regulation of cell growth; cell differentiation; proteolysis
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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