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PAX5 peptide :: PAX5 / BSAP Peptide

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Catalog # MBS425077
Unit / Price
  0.1 mg  /  $190 +1 FREE 8GB USB
PAX5 peptide
Product Name

PAX5 / BSAP, Peptide

Also Known As

PAX5 / BSAP Immunizing Peptide

Product Synonym Names
PAX5; BSAP; paired box gene 5 (B-cell lineage specific activator protein); B-cell lineage specific activator protein; paired box homeotic gene 5 (B-cell lineage specific activator protein); paired box 5; B cell specific activator protein; B-cell lineage s; PAX5 / BSAP
Product Gene Name
Product Synonym Gene Name
Antibody/Peptide Pairs
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Length
391
Sequence
DLEKNYPTPR TSR-C
OMIM
167414
Species Reactivity
Human, Mouse
Form/Format
100ug of dried peptide
Preparation and Storage
Shipped at ambient temperature, store at -20 degree C
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Other Notes
Small volumes of PAX5 peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for PAX5. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
34,132 Da
NCBI Official Full Name
paired box protein Pax-5 isoform 1
NCBI Official Synonym Full Names
paired box 5
NCBI Official Symbol
NCBI Official Synonym Symbols
ALL3; BSAP
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NCBI Protein Information
paired box protein Pax-5
UniProt Protein Name
Paired box protein Pax-5
UniProt Synonym Protein Names
B-cell-specific transcription factor; BSAP
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
UniProt Entry Name
PAX5_HUMAN
NCBI Summary for PAX5
This gene encodes a member of the paired box (PAX) family of transcription factors. The central feature of this gene family is a novel, highly conserved DNA-binding motif, known as the paired box. Paired box transcription factors are important regulators in early development, and alterations in the expression of their genes are thought to contribute to neoplastic transformation. This gene encodes the B-cell lineage specific activator protein that is expressed at early, but not late stages of B-cell differentiation. Its expression has also been detected in developing CNS and testis and so the encoded protein may also play a role in neural development and spermatogenesis. This gene is located at 9p13, which is involved in t(9;14)(p13;q32) translocations recurring in small lymphocytic lymphomas of the plasmacytoid subtype, and in derived large-cell lymphomas. This translocation brings the potent E-mu enhancer of the IgH gene into close proximity of the PAX5 promoter, suggesting that the deregulation of transcription of this gene contributes to the pathogenesis of these lymphomas. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013]
UniProt Comments for PAX5
PAX5: May play an important role in B-cell differentiation as well as neural development and spermatogenesis. Involved in the regulation of the CD19 gene, a B-lymphoid-specific target gene. Interacts with DAXX. Binds DNA as a monomer. Binds TLE4.

Protein type: Oncoprotein

Chromosomal Location of Human Ortholog: 9p13

Molecular Function: protein binding

Biological Process: humoral immune response; multicellular organismal development; organ morphogenesis; transcription from RNA polymerase II promoter

Disease: Leukemia, Acute Lymphoblastic, Susceptibility To, 3
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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