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PBRM1 elisa kit :: Human Polybromo 1 (PBRM1) ELISA Kit

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Catalog # MBS9312028
Unit / Price
  48-Strip-Wells  /  $470 +1 FREE 8GB USB
  96-Strip-Wells  /  $680 +1 FREE 8GB USB
  5x96-Strip-Wells  /  $3,100 +3 FREE 8GB USB
  10x96-Strip-Wells  /  $6,095 +7 FREE 8GB USB
PBRM1 elisa kit
Product Name

Polybromo 1 (PBRM1), ELISA Kit

Also Known As

Human Polybromo 1 (PBRM1) ELISA Kit

Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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Chromosome Location
Chromosome: 3; NC_000003.11 (52579368..52719866, complement). Location: 3p21
OMIM
144700
3D Structure
ModBase 3D Structure for Q86U86
Species Reactivity
Preparation and Storage
Store all reagents at 2-8 degree C
Product Note
Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
Other Notes
Small volumes of PBRM1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms forPBRM1purchase
MBS9312028 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Polybromo 1 (PBRM1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing PBRM1. The ELISA analytical biochemical technique of the MBS9312028 kit is based on PBRM1 antibody-PBRM1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect PBRM1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, PBRM1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
NCBI/Uniprot data below describe general gene information for PBRM1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
192,948 Da
NCBI Official Full Name
protein polybromo-1
NCBI Official Synonym Full Names
polybromo 1
NCBI Official Symbol
PBRM1  [Similar Products]
NCBI Official Synonym Symbols
PB1; BAF180
  [Similar Products]
NCBI Protein Information
protein polybromo-1; polybromo-1D; BRG1-associated factor 180
UniProt Protein Name
Protein polybromo-1
UniProt Synonym Protein Names
BRG1-associated factor 180; BAF180; Polybromo-1D
Protein Family
UniProt Gene Name
PBRM1  [Similar Products]
UniProt Synonym Gene Names
BAF180; PB1; hPB1; BAF180  [Similar Products]
UniProt Entry Name
PB1_HUMAN
NCBI Summary for PBRM1
This locus encodes a subunit of ATP-dependent chromatin-remodeling complexes. The encoded protein has been identified as in integral component of complexes necessary for ligand-dependent transcriptional activation by nuclear hormone receptors. Mutations at this locus have been associated with primary clear cell renal cell carcinoma. [provided by RefSeq, Feb 2012]
UniProt Comments for PBRM1
polybromo 1: Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Acts as a negative regulator of cell proliferation. Defects in PBRM1 are a cause of renal cell carcinoma (RCC). It is a heterogeneous group of sporadic or hereditary carcinoma derived from cells of the proximal renal tubular epithelium. It is subclassified into clear cell renal carcinoma (non-papillary carcinoma), papillary renal cell carcinoma, chromophobe renal cell carcinoma, collecting duct carcinoma with medullary carcinoma of the kidney, and unclassified renal cell carcinoma. 9 isoforms of the human protein are produced by alternative splicing.

Protein type: DNA-binding; Tumor suppressor

Chromosomal Location of Human Ortholog: 3p21

Cellular Component: kinetochore; nuclear chromosome

Molecular Function: protein binding; DNA binding; chromatin binding

Biological Process: chromatin remodeling; mitosis; negative regulation of cell proliferation; regulation of transcription, DNA-dependent; transcription, DNA-dependent; heart development; placenta development
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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