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PCII elisa kit :: Sheep Procollagen II ELISA Kit

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Catalog # MBS083854
Unit / Price
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  48-Strip-Wells  /  $470 +1 FREE 8GB USB
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PCII elisa kit
Product Name

Procollagen II (PCII), ELISA Kit

Full Product Name

Sheep Procollagen II ELISA Kit

Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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3D Structure
ModBase 3D Structure for P05539
Species Reactivity
Preparation and Storage
Store all reagents at 2-8 degree C
Product Note
Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
Other Notes
Small volumes of PCII elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for PCIIpurchase
MBS083854 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Procollagen II (PCII) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing PCII. The ELISA analytical biochemical technique of the MBS083854 kit is based on PCII antibody-PCII antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect PCII antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, PCII. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
NCBI/Uniprot data below describe general gene information for PCII. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
134,570 Da
NCBI Official Full Name
procollagen, type II, alpha 1, isoform CRA_c
NCBI Official Synonym Full Names
collagen, type II, alpha 1
NCBI Official Symbol
Col2a1  [Similar Products]
NCBI Official Synonym Symbols
CG2A1A; COLLII
  [Similar Products]
NCBI Protein Information
collagen alpha-1(II) chain; collagen alpha-1(II) chain; Procollagen II alpha 1; alpha-1 type II collagen; procollagen, type II, alpha 1; collagen type II (Col2A1) gene, enhancer region
UniProt Protein Name
Collagen alpha-1(II) chain
UniProt Synonym Protein Names
Alpha-1 type II collagen
UniProt Gene Name
Col2a1  [Similar Products]
UniProt Entry Name
CO2A1_RAT
NCBI Summary for PCII
structural component of the cartilage extracellular matrix [RGD, Feb 2006]
UniProt Comments for PCII
Function: Type II collagen is specific for cartilaginous tissues. It is essential for the normal embryonic development of the skeleton, for linear growth and for the ability of cartilage to resist compressive forces.

Subunit structure: Homotrimers of alpha 1(II) chains.

Subcellular location: Secreted › extracellular space › extracellular matrix

By similarity.

Tissue specificity: Expressed in chondrocytes. Ref.5

Domain: The C-terminal propeptide, also known as COLFI domain, have crucial roles in tissue growth and repair by controlling both the intracellular assembly of procollagen molecules and the extracellular assembly of collagen fibrils. It binds a calcium ion which is essential for its function

By similarity.

Post-translational modification: Prolines at the third position of the tripeptide repeating unit (G-X-P) are hydroxylated in some or all of the chains. Probably 3-hydroxylated on Pro-602, Pro-839, Pro-1076, Pro-1133, Pro-1139 and Pro-1145 by LEPREL1.

Sequence similarities: Belongs to the fibrillar collagen family.Contains 1 fibrillar collagen NC1 domain.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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