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PDCD1LG2 blocking peptide :: PDL-2 Blocking Peptide

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Catalog # MBS153072
Unit / Price
  0.05 mg  /  $140 +1 FREE 8GB USB
PDCD1LG2 blocking peptide
Product Name

PDL-2 (PDCD1LG2), Blocking Peptide

Full Product Name

PDL-2 Peptide

Product Synonym Names
B7DC; Btdc; PDL2; CD273; PD-L2; PDCD1L2; bA574F11.2; B7DC; Programmed cell death 1 ligand 2; Butyrophilin B7-DC; PD-1 ligand 2; programmed cell death 1 ligand 2
Antibody/Peptide Pairs
PDL-2 peptide (MBS153072) is used for blocking the activity of PDL-2 antibody (MBS151188)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
605723
3D Structure
ModBase 3D Structure for Q9BQ51
Form/Format
Liquid
Concentration
200 ug/mL (lot specific)
Species
Human
Buffer
PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide
Location
16 amino acids near the center of human PDL-2
Preparation and Storage
Store PDL-2 peptide at -20 degree C, stable for one year.
Other Notes
Small volumes of PDCD1LG2 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for PDCD1LG2 blocking peptide
Blocking (BL)
Application Notes for PDCD1LG2 blocking peptide
The peptide is used for blocking the activity of PDL-2 antibody.
NCBI/Uniprot data below describe general gene information for PDCD1LG2. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
20,745 Da
NCBI Official Full Name
programmed cell death 1 ligand 2
NCBI Official Synonym Full Names
programmed cell death 1 ligand 2
NCBI Official Symbol
PDCD1LG2  [Similar Products]
NCBI Official Synonym Symbols
B7DC; Btdc; PDL2; CD273; PD-L2; PDCD1L2; bA574F11.2
  [Similar Products]
NCBI Protein Information
programmed cell death 1 ligand 2; B7-DC; PD-1 ligand 2; PD-1-ligand 2; PDCD1 ligand 2; butyrophilin B7-DC; programmed death ligand 2; B7 dendritic cell molecule
UniProt Protein Name
Programmed cell death 1 ligand 2
UniProt Synonym Protein Names
Butyrophilin B7-DC; B7-DC; CD_antigen: CD273
Protein Family
UniProt Gene Name
PDCD1LG2  [Similar Products]
UniProt Synonym Gene Names
B7DC; CD273; PDCD1L2; PDL2; PD-1 ligand 2; PD-L2; PDCD1 ligand 2; Programmed death ligand 2; B7-DC  [Similar Products]
UniProt Entry Name
PD1L2_HUMAN
UniProt Comments for PDCD1LG2
PDCD1LG2: Involved in the costimulatory signal, essential for T- cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production. Belongs to the immunoglobulin superfamily. BTN/MOG family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Receptor, misc.; Membrane protein, integral

Chromosomal Location of Human Ortholog: 9p24.2

Cellular Component: plasma membrane; integral to membrane; endomembrane system

Biological Process: negative regulation of interleukin-10 production; negative regulation of interferon-gamma production; negative regulation of activated T cell proliferation; T cell costimulation; positive regulation of T cell proliferation; immune response
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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