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PDCD4 elisa kit :: Rat programmed cell death 4 (neoplastic transformation inhibitor) ELISA Kit

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Catalog # MBS9320293
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  48-Strip-Wells  /  $470 +1 FREE 8GB USB
  96-Strip-Wells  /  $680 +1 FREE 8GB USB
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PDCD4 elisa kit
Product Name

programmed cell death 4 (neoplastic transformation inhibitor) (PDCD4), ELISA Kit

Full Product Name

Rat Programmed cell death protein 4, PDCD4 ELISA Kit

Product Synonym Names
Rat Programmed cell death protein 4 (PDCD4) ELISA kit; RP11-348N5.4; H731; MGC33046; MGC33047; nuclear antigen H731; programmed cell death 4; programmed cell death 4 (neoplastic transformation inhibitor)
Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Request for Current Manual Insert
3D Structure
ModBase 3D Structure for Q9JID1
Species Reactivity
Preparation and Storage
Store all reagents at 2-8 degree C
Product Note
Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
Other Notes
Small volumes of PDCD4 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for PDCD4purchase
MBS9320293 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the programmed cell death 4 (neoplastic transformation inhibitor) (PDCD4) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing PDCD4. The ELISA analytical biochemical technique of the MBS9320293 kit is based on PDCD4 antibody-PDCD4 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect PDCD4 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, PDCD4. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
NCBI/Uniprot data below describe general gene information for PDCD4. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Related Accession #
Molecular Weight
51,736 Da
NCBI Official Full Name
programmed cell death protein 4
NCBI Official Synonym Full Names
programmed cell death 4
NCBI Official Symbol
Pdcd4  [Similar Products]
NCBI Official Synonym Symbols
NCBI Protein Information
programmed cell death protein 4; death-upregulated; death up-regulated gene protein
UniProt Protein Name
Programmed cell death protein 4
UniProt Synonym Protein Names
Death up-regulated gene protein
UniProt Gene Name
Pdcd4  [Similar Products]
UniProt Synonym Gene Names
UniProt Entry Name
PDCD4_RAT
NCBI Summary for PDCD4
acts as an inhibitor of apoptosis; has similarity to eukaryotic translation initiation factor (eIF)4G [RGD, Feb 2006]
UniProt Comments for PDCD4
PDCD4: protein localized to the nucleus in proliferating cells that seems to possess a tumor suppressor activity. Directly interacts with the RNA helicase eIF4A and inhibits protein synthesis by interfering with the assembly of the cap-dependent translation initiation complex. Suppresses carbonic anhydrase type II protein expression in carcinoid cell lines. Since tumor cells require a high bicarbonate flux for their growth, carbonic anhydrase suppression results in growth inhibition. Expression of this gene is modulated by cytokines in natural killer and T cells. The gene product is thought to play a role in apoptosis but the specific role has not yet been determined. Two differentially spliced isoforms have been identified.

Protein type: Tumor suppressor; Apoptosis

Cellular Component: nucleoplasm; cytoplasm; nucleus; cytosol

Molecular Function: RNA binding

Biological Process: negative regulation of JNK activity; apoptosis; regulation of protein metabolic process; cell aging; negative regulation of transcription, DNA-dependent; negative regulation of apoptosis
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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