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PDGFB recombinant protein :: Platelet-derived growth factor subunit B (PDGFB) Recombinant Protein

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Catalog # MBS1400854
Unit / Price
  0.05 mg (E-Coli)  /  $560 +1 FREE 8GB USB
  0.2 mg (E-Coli)  /  $745 +1 FREE 8GB USB
  0.5 mg (E-Coli)  /  $820 +1 FREE 8GB USB
  0.05 mg (Baculovirus)  /  $870 +1 FREE 8GB USB
  0.2 mg (Yeast)  /  $970 +1 FREE 8GB USB
  0.5 mg (Yeast)  /  $1,085 +1 FREE 8GB USB
  0.1 mg (Baculovirus)  /  $1,090 +1 FREE 8GB USB
  0.05 mg (Mammalian-Cell)  /  $1,105 +1 FREE 8GB USB
  1 mg (E-Coli)  /  $1,155 +1 FREE 8GB USB
  0.5 mg (Baculovirus)  /  $1,580 +1 FREE 8GB USB
  1 mg (Yeast)  /  $1,650 +2 FREE 8GB USB
  0.1 mg (Mammalian-Cell)  /  $1,685 +2 FREE 8GB USB
  1 mg (Baculovirus)  /  $2,115 +2 FREE 8GB USB
PDGFB recombinant protein
Product Name

Platelet-derived growth factor subunit B (PDGFB), Recombinant Protein

Also Known As

Recombinant Dog Platelet-derived growth factor subunit B (PDGFB)

Product Synonym Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
82-242aa, Full Length of Mature Protein
Sequence Length
242
Sequence
SLGSPTVAEP AMIAECKTRT EVFEISRRLI DRTNANFLVW PPCVEVQRCS GCCNNRNVQC RPTQVQLRPV QVRKIEIVRK KPTFKKATVT LEDHLACKCE TVVAARPVTR TPGSSQDLRA AKTPQTRVTI RTVRVRRPPK GKHRKFKHTH DKKALKETLG A
3D Structure
ModBase 3D Structure for Q6Q7I7
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Species
Canis familiaris (Dog) (Canis lupus familiaris)
Storage Buffer
Tris-based buffer, 50% glycerol
Tag Information
Tag type will be determined during the manufacturing process
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of PDGFB recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
PDGFB recombinant protein
This protein is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. This gene product can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma. Reciprocal translocations between chromosomes 22 and 7, at sites where this gene and that for COL1A1 are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans resulting from unregulated expression of growth factor. Two alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
NCBI/Uniprot data below describe general gene information for PDGFB. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Related Accession #
Molecular Weight
27,413 Da
NCBI Official Full Name
platelet-derived growth factor subunit B
NCBI Official Synonym Full Names
platelet derived growth factor subunit B
NCBI Official Symbol
PDGFB  [Similar Products]
NCBI Official Synonym Symbols
PDGF-B
  [Similar Products]
NCBI Protein Information
platelet-derived growth factor subunit B
UniProt Protein Name
Platelet-derived growth factor subunit B
UniProt Synonym Protein Names
PDGF-2; Platelet-derived growth factor B chain; Platelet-derived growth factor beta polypeptide
UniProt Gene Name
PDGFB  [Similar Products]
UniProt Synonym Gene Names
PDGF subunit B  [Similar Products]
UniProt Comments for PDGFB
Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Required for normal proliferation and recruitment of pericytes and vascular smooth muscle cells in the central nervous system, skin, lung, heart and placenta. Required for normal blood vessel development, and for normal development of kidney glomeruli. Plays an important role in wound healing. Signaling is modulated by the formation of heterodimers with PDGFA ().
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Organs/Tissues associated with PDGFB recombinant protein
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