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Pdk1 recombinant protein :: [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1, mitochondrial (Pdk1) Recombinant Protein

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Catalog # MBS1317979
Unit / Price
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  0.01 mg (Baculovirus)  /  $255 +1 FREE 8GB USB
  0.02 mg (Baculovirus)  /  $395 +1 FREE 8GB USB
  0.05 mg (Baculovirus)  /  $755 +1 FREE 8GB USB
  0.1 mg (Baculovirus)  /  $1,040 +1 FREE 8GB USB
  0.5 mg (Baculovirus)  /  $1,480 +1 FREE 8GB USB
  1 mg (Baculovirus)  /  $2,060 +2 FREE 8GB USB
SDS-Page
Product Name

[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1, mitochondrial (Pdk1), Recombinant Protein

Popular Item
Full Product Name

Recombinant Mouse [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1, mitochondrial (Pdk1)

Product Synonym Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
MBS1317979 COA
Sequence Positions
27-434aa, Full Length of Mature Protein
Sequence
ASASASGSGP ASELGVPGQV DFYARFSPSP LSMKQFLDFG SVNACEKTSF MFLRQELPVR LANIMKEISL LPDNLLRTPS VQLVQSWYIQ SLQELLDFKD KSAEDAKTIY EFTDTVIRIR NRHNDVIPTM AQGVTEYKES FGVDPVTSQN VQYFLDRFYM SRISIRMLLN QHSLLFGGKG SPSHRKHIGS INPNCDVVEV IKDGYENARR LCDLYYVNSP ELELEELNAK SPGQTIQVVY VPSHLYHMVF ELFKNAMRAT MEHHADKGVY PPIQVHVTLG EEDLTVKMSD RGGGVPLRKI DRLFNYMYST APRPRVETSR AVPLAGFGYG LPISRLYAQY FQGDLKLYSL EGYGTDAVIY IKALSTESVE RLPVYNKAAW KHYKANHEAD DWCVPSREPK DMTTFRSS
3D Structure
ModBase 3D Structure for Q8BFP9
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Species
Mouse
Storage Buffer
Tris-based buffer, 50% glycerol
Tag Information
Tag type will be determined during the manufacturing process
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of Pdk1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
Pdk1 recombinant protein
Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation
dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation.

Pdk1 recombinant protein SDS-Page image
(Note: Representative image, actual molecular weight may vary depending on Tag type and expression host)
NCBI/Uniprot data below describe general gene information for Pdk1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
48,995 Da
NCBI Official Full Name
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial isoform 1
NCBI Official Synonym Full Names
pyruvate dehydrogenase kinase, isoenzyme 1
NCBI Official Symbol
NCBI Official Synonym Symbols
B830012B01; D530020C15Rik
  [Similar Products]
NCBI Protein Information
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial; pyruvate dehydrogenase kinase, isozyme 1
UniProt Protein Name
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial
UniProt Synonym Protein Names
Pyruvate dehydrogenase kinase isoform 1; PDH kinase 1
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
PDH kinase 1  [Similar Products]
UniProt Comments for Pdk1
Kinase that plays a key role in regulation of glucose and fatty acid metabolism and homeostasis via phosphorylation of the pyruvate dehydrogenase subunits PDHA1 and PDHA2. This inhibits pyruvate dehydrogenase activity, and thereby regulates metabolite flux through the tricarboxylic acid cycle, down-regulates aerobic respiration and inhibits the formation of acetyl-coenzyme A from pyruvate. Plays an important role in cellular responses to hypoxia and is important for cell proliferation under hypoxia. Protects cells against apoptosis in response to hypoxia and oxidative stress ().
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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