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PERP recombinant protein :: p53 apoptosis effector related to PMP-22 (PERP) Recombinant Protein

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Catalog # MBS7025488
Unit / Price
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  0.01 mg  /  $425 +1 FREE 8GB USB
  0.05 mg  /  $675 +1 FREE 8GB USB
  0.1 mg  /  $1,130 +1 FREE 8GB USB
SDS-Page
Product Name

p53 apoptosis effector related to PMP-22 (PERP), Recombinant Protein

Popular Item
Full Product Name

Recombinant Human p53 apoptosis effector related to PMP-22 (PERP)

Product Synonym Gene Name
KCP1; KRTCAP1; PIGPC1; THW[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
MBS7025488 COA
Sequence Positions
1-193aa; Full Length
Sequence
MIRCGLACER CRWILPLLLL SAIAFDIIAL AGRGWLQSSD HGQTSSLWWK CSQEGGGSGS YEEGCQSLME YAWGRAAAAM LFCGFIILVI CFILSFFALC GPQMLVFLRV IGGLLALAAV FQIISLVIYP VKYTQTFTLH ANPAVTYIYN WAYGFGWAAT IILIGCAFFF CCLPNYEDDL LGNAKPRYFY TSA
OMIM
609301
3D Structure
ModBase 3D Structure for Q96FX8
Host
Cell Free Expression
Purity/Purification
Greater than 85% as determined by SDS-PAGE. (lot specific)
Form/Format
Liquid containing glycerol
Species
Human
Storage Buffer
Tris-based buffer, 50% glycerol.
Production Note
Special Offer: The Cell Free host-expressed protein is manufactured from a stock plasmid containing the protein gene. Cell Freehost-expressed protein is stocked in different unit sizes ranging from as small as 10 ug to as large as 1 mg. Bulk inventory is also available. The Cell Free host-expressed protein has been ordered over and over again by researchers and has stood the test of time as both a robust protein and important target for the research community. It is part of our new program to make our most popular protein targets and corresponding hosts available in expanded unit sizes and with a quick processing time. Select Cell Free host-expressed protein for the fastest delivery among all hosts. Please contact our technical support team or email to support@mybiosource.com for more details.
Preparation and Storage
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of PERP recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
PERP recombinant protein
Component of intercellular desmosome junctions. Plays a role in stratified epithelial integrity and cell-cell adhesion by promoting desmosome assembly. Plays a role as an effector in the TP53-dependent apoptotic pathway
Product Categories/Family for PERP recombinant protein
Application Notes for PERP recombinant protein
This is a recombinant transmembrane protein expressed in a cell-free expression system.

PERP recombinant protein SDS-Page image
(Note: Representative image, actual molecular weight may vary depending on Tag type and expression host)
NCBI/Uniprot data below describe general gene information for PERP. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
21,386 Da
NCBI Official Full Name
p53 apoptosis effector related to PMP-22
NCBI Official Synonym Full Names
PERP, TP53 apoptosis effector
NCBI Official Symbol
NCBI Official Synonym Symbols
THW; KCP1; PIGPC1; KRTCAP1; dJ496H19.1
  [Similar Products]
NCBI Protein Information
p53 apoptosis effector related to PMP-22
UniProt Protein Name
p53 apoptosis effector related to PMP-22
UniProt Synonym Protein Names
Keratinocyte-associated protein 1; KCP-1; P53-induced protein PIGPC1; Transmembrane protein THW
UniProt Gene Name
UniProt Synonym Gene Names
KCP1; KRTCAP1; PIGPC1; THW; KCP-1  [Similar Products]
UniProt Entry Name
PERP_HUMAN
UniProt Comments for PERP
PERP: Component of intercellular desmosome junctions. Plays a role in stratified epithelial integrity and cell-cell adhesion by promoting desmosome assembly. Plays a role as an effector in the TP53-dependent apoptotic pathway. Belongs to the TMEM47 family.

Protein type: Mitochondrial; Membrane protein, multi-pass; Membrane protein, integral; Cell adhesion

Chromosomal Location of Human Ortholog: 6q24

Cellular Component: cell junction; desmosome; Golgi apparatus; integral to plasma membrane; mitochondrion; plasma membrane

Biological Process: heterotypic cell-cell adhesion; Notch signaling pathway; positive regulation of proteolysis; regulation of apoptosis
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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