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PFDN1 recombinant protein

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Catalog # MBS203820
Unit / Price
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  0.01 mg  /  $310 +1 FREE 8GB USB
  0.05 mg  /  $720 +1 FREE 8GB USB
SDS-Page
Product Name

PFDN1, Recombinant Protein

Full Product Name

PFDN1, 14-122aa, Human, His tag, E Coli

Product Synonym Names
Prefoldin subunit 1; PDF; PFD1
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
MGSSHHHHHH SSGLVPRGSH MTELQAKVID TQQKVKLADI QIEQLNRTKK HAHLTDTEIM TLVDETNMYE GVGRMFILQS KEAIHSQLLE KQKIAEEKIK ELEQKKSYLE RSVKEAEDNI REMLMARRAQ
OMIM
Y17392 mRNA
3D Structure
ModBase 3D Structure for O60925
Host
E Coli
Purity/Purification
> 90% by SDS-PAGE
Form/Format
Liquid. In 20 mM Tris-HCl Buffer (pH 8.0) containing 20% glycerol
Concentration
0.5 mg/ml (determined by Bradford assay) (lot specific)
Antigen Species
Human
Tag Information
His-tag
Preparation and Storage
Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
Other Notes
Small volumes of PFDN1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
PFDN1 recombinant protein
PFDN1 is one of sixsubunits of prefoldin, a heterohexameric chaperone protein which assists in the correct folding of other proteins. This protein delivers nonnative target proteins, principally actins and tubulins, to the eukaryotic cytosolic chaperonin for facilitated folding. Defects in PFDN1 displayed phenotypes characteristic of defects in cytoskeletal function, including manifestations of ciliary dyskinesia, neuronal loss, and defects in B and T cell development and function. Recombinant human PFDN1 protein, fused to His-tag at N-terminus, was expressed in E Coli and purified by using conventional chromatography.
Product Categories/Family for PFDN1 recombinant protein
Applications Tested/Suitable for PFDN1 recombinant protein
SDS-PAGE

NCBI/Uniprot data below describe general gene information for PFDN1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
15.0kDa (130aa), confirmed by MALDI-TOF
NCBI Official Full Name
prefoldin subunit 1
NCBI Official Synonym Full Names
prefoldin subunit 1
NCBI Official Symbol
PFDN1  [Similar Products]
NCBI Official Synonym Symbols
PDF; PFD1
  [Similar Products]
NCBI Protein Information
prefoldin subunit 1
UniProt Protein Name
Prefoldin subunit 1
Protein Family
UniProt Gene Name
PFDN1  [Similar Products]
UniProt Synonym Gene Names
NCBI Summary for PFDN1
This gene encodes a member of the prefoldin beta subunit family. The encoded protein is one of six subunits of prefoldin, a molecular chaperone complex that binds and stabilizes newly synthesized polypeptides, thereby allowing them to fold correctly. The complex, consisting of two alpha and four beta subunits, forms a double beta barrel assembly with six protruding coiled-coils. [provided by RefSeq, Jul 2008]
UniProt Comments for PFDN1
Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.
Product References and Citations for PFDN1 recombinant protein
Ruley HE., et al. (2008) J Immunol. 181 (1):476-84.; Cowan NJ., et al (2004) J Biol Chem. 279 (6):4196-203.;

Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Products associated with PFDN1 recombinant protein
Diseases associated with PFDN1 recombinant protein
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