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PFKL recombinant protein :: 6-phosphofructokinase, liver type (PFKL) Recombinant Protein

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Catalog # MBS964737
Unit / Price
Scan QR to view Datasheet
  0.05 mg (Yeast)  /  $1,210 +1 FREE 8GB USB
  0.05 mg (E-Coli)  /  $1,215 +1 FREE 8GB USB
  0.05 mg (Baculovirus)  /  $1,450 +1 FREE 8GB USB
  0.2 mg (E-Coli)  /  $1,640 +2 FREE 8GB USB
  0.2 mg (Yeast)  /  $1,650 +2 FREE 8GB USB
  0.05 mg (Mammalian-Cell)  /  $1,690 +2 FREE 8GB USB
  0.5 mg (E-Coli)  /  $1,810 +2 FREE 8GB USB
  0.5 mg (Yeast)  /  $1,870 +2 FREE 8GB USB
  0.1 mg (Baculovirus)  /  $2,095 +2 FREE 8GB USB
  0.5 mg (Baculovirus)  /  $2,685 +3 FREE 8GB USB
  0.1 mg (Mammalian-Cell)  /  $2,695 +3 FREE 8GB USB
  1 mg (E-Coli)  /  $2,730 +3 FREE 8GB USB
  1 mg (Yeast)  /  $2,950 +3 FREE 8GB USB
  1 mg (Baculovirus)  /  $4,145 +5 FREE 8GB USB
PFKL recombinant protein
Product Name

6-phosphofructokinase, liver type (PFKL), Recombinant Protein

Full Product Name

Recombinant Human 6-phosphofructokinase, liver type (PFKL)

Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
2-780aa, Full Length of Mature Protein
Sequence
AAVDLEKLRA SGAGKAIGVL TSGGDAQGMN AAVRAVTRMG IYVGAKVFLI YEGYEGLVEG GENIKQANWL SVSNIIQLGG TIIGSARCKA FTTREGRRAA AYNLVQHGIT NLCVIGGDGS LTGANIFRSE WGSLLEELVA EGKISETTAR TYSHLNIAGL VGSIDNDFCG TDMTIGTDSA LHRIMEVIDA ITTTAQSHQR TFVLEVMGRH CGYLALVSAL ASGADWLFIP EAPPEDGWEN FMCERLGETR SRGSRLNIII IAEGAIDRNG KPISSSYVKD LVVQRLGFDT RVTVLGHVQR GGTPSAFDRI LSSKMGMEAV MALLEATPDT PACVVTLSGN QSVRLPLMEC VQMTKEVQKA MDDKRFDEAT QLRGGSFENN WNIYKLLAHQ KPPKEKSNFS LAILNVGAPA AGMNAAVRSA VRTGISHGHT VYVVHDGFEG LAKGQVQEVG WHDVAGWLGR GGSMLGTKRT LPKGQLESIV ENIRIYGIHA LLVVGGFEAY EGVLQLVEAR GRYEELCIVM CVIPATISNN VPGTDFSLGS DTAVNAAMES CDRIKQSASG TKRRVFIVET MGGYCGYLAT VTGIAVGADA AYVFEDPFNI HDLKVNVEHM TEKMKTDIQR GLVLRNEKCH DYYTTEFLYN LYSSEGKGVF DCRTNVLGHL QQGGAPTPFD RNYGTKLGVK AMLWLSEKLR EVYRKGRVFA NAPDSACVIG LKKKAVAFSP VTELKKDTDF EHRMPREQWW LSLRLMLKML AQYRISMAAY VSGELEHVTR RTLSMDKGF
OMIM
171860
3D Structure
ModBase 3D Structure for P17858
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Species
Human
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of PFKL recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
PFKL recombinant protein
Phosphofructokinase (PFK) is a tetrameric enzyme that catalyzes a key step in glycolysis, namely the conversion of D-fructose 6-phosphate to D-fructose 1,6-bisphosphate. Separate genes encode a muscle subunit (M) and a liver subunit (L). PFK from muscle is a homotetramer of M subunits, PFK from liver is a homotetramer of L-subunits, while PFK from platelets can be composed of any tetrameric combination of M and L subunits. This protein represents the L subunit. Alternate splicing results in two transcript variants, one of which is a candidate for nonsense-mediated decay (NMD).
NCBI/Uniprot data below describe general gene information for PFKL. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
90,203 Da
NCBI Official Full Name
ATP-dependent 6-phosphofructokinase, liver type isoform a
NCBI Official Synonym Full Names
phosphofructokinase, liver type
NCBI Official Symbol
NCBI Official Synonym Symbols
PFK-B; PFK-L; ATP-PFK
  [Similar Products]
NCBI Protein Information
ATP-dependent 6-phosphofructokinase, liver type
UniProt Protein Name
ATP-dependent 6-phosphofructokinase, liver type
UniProt Synonym Protein Names
6-phosphofructokinase type B; Phosphofructo-1-kinase isozyme B; PFK-B; Phosphohexokinase
UniProt Gene Name
UniProt Synonym Gene Names
ATP-PFK; PFK-L  [Similar Products]
NCBI Summary for PFKL
This gene encodes the liver (L) subunit of an enzyme that catalyzes the conversion of D-fructose 6-phosphate to D-fructose 1,6-bisphosphate, which is a key step in glucose metabolism (glycolysis). This enzyme is a tetramer that may be composed of different subunits encoded by distinct genes in different tissues. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]
UniProt Comments for PFKL
Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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