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PGK1 recombinant protein :: Phosphoglycerate kinase 1 Recombinant Protein

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Catalog # MBS717266 (PROMOTIONAL PRICING: 10% OFF web price. Discount is not applicable for bulk pricing such as 5x96T or 10x96T. Discount will be applied after order has been placed)
Unit / Price
  0.01 mg  /  $110 +1 FREE 8GB USB
  0.05 mg  /  $190 +1 FREE 8GB USB
  0.1 mg  /  $285 +1 FREE 8GB USB
  0.2 mg  /  $460 +1 FREE 8GB USB
  0.5 mg  /  $750 +1 FREE 8GB USB
  1 mg  /  $1,180 +1 FREE 8GB USB
SDS-PAGE
Product Name

Phosphoglycerate kinase 1 (PGK1), Recombinant Protein

Popular Item
Also Known As

Recombinant Human Phosphoglycerate kinase 1

Product Synonym Names
Cell migration-inducing gene 10 protein; Primer recognition protein 2; PRP 2
Product Synonym Gene Name
PGKA; MIG10; OK; SW-cl.110[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
25-417aa; Partial
Sequence Length
417
Sequence
FNVPMKNNQI TNNQRIKAAV PSIKFCLDNG AKSVVLMSHL GRPDGVPMPD KYSLEPVAVE LKSLLGKDVL FLKDCVGPEV EKACANPAAG SVILLENLRF HVEEEGKGKD ASGNKVKAEP AKIEAFRASL SKLGDVYVND AFGTAHRAHS SMVGVNLPQK AGGFLMKKEL NYFAKALESP ERPFLAILGG AKVADKIQLI NNMLDKVNEM IIGGGMAFTF LKVLNNMEIG TSLFDEEGAK IVKDLMSKAE KNGVKITLPV DFVTADKFDE NAKTGQATVA SGIPAGWMGL DCGPESSKKY AEAVTRAKQI VWNGPVGVFE WEAFARGTKA LMDEVVKATS RGCITIIGGG DTATCCAKWN TEDKVSHVST GGGASLELLE GKVLPGVDAL SNI
OMIM
300653
3D Structure
ModBase 3D Structure for P00558
Host
E Coli
Purity/Purification
Greater than 90% as determined by SDS-PAGE. (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Preparation and Storage
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of PGK1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
PGK1 recombinant protein
In addition to its role as a glycolytic enzyme, it ses that PGK-1 acts as a polymerase alpha cofactor protein (primer recognition protein).
Product Categories/Family for PGK1 recombinant protein

PGK1 recombinant protein SDS-PAGE image
(Note: Representative image, actual molecular weight may vary depending on Tag type and expression host)
NCBI/Uniprot data below describe general gene information for PGK1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
69.3kD
NCBI Official Full Name
phosphoglycerate kinase 1
NCBI Official Synonym Full Names
phosphoglycerate kinase 1
NCBI Official Symbol
NCBI Official Synonym Symbols
PGKA; MIG10; HEL-S-68p
  [Similar Products]
NCBI Protein Information
phosphoglycerate kinase 1
UniProt Protein Name
Phosphoglycerate kinase 1
UniProt Synonym Protein Names
Cell migration-inducing gene 10 protein; Primer recognition protein 2; PRP 2
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
PGKA; PRP 2  [Similar Products]
UniProt Entry Name
PGK1_HUMAN
NCBI Summary for PGK1
The protein encoded by this gene is a glycolytic enzyme that catalyzes the conversion of 1,3-diphosphoglycerate to 3-phosphoglycerate. The encoded protein may also act as a cofactor for polymerase alpha. Additionally, this protein is secreted by tumor cells where it participates in angiogenesis by functioning to reduce disulfide bonds in the serine protease, plasmin, which consequently leads to the release of the tumor blood vessel inhibitor angiostatin. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Deficiency of the enzyme is associated with a wide range of clinical phenotypes hemolytic anemia and neurological impairment. Pseudogenes of this gene have been defined on chromosomes 19, 21 and the X chromosome. [provided by RefSeq, Jan 2014]
UniProt Comments for PGK1
PGK1: an apparent multifunctional protein. A glycolytic enzyme and a polymerase alpha cofactor protein (primer recognition protein).

Protein type: Kinase, other; EC 2.7.2.3; Carbohydrate Metabolism - glycolysis and gluconeogenesis

Chromosomal Location of Human Ortholog: Xq13.3

Cellular Component: cytosol; lipid raft; membrane

Molecular Function: ATP binding; phosphoglycerate kinase activity; protein binding

Biological Process: carbohydrate metabolic process; epithelial cell differentiation; gluconeogenesis; glucose metabolic process; phosphorylation

Disease: Phosphoglycerate Kinase 1 Deficiency
Product References and Citations for PGK1 recombinant protein
Isolation and DNA sequence of a full-length cDNA clone for human X chromosome-encoded phosphoglycerate kinase.Michelson A.M., Markham A.F., Orkin S.H.Proc. Natl. Acad. Sci. U.S.A. 80:472-476(1983)

Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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