• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

PGLYRP4 blocking peptide

Scan QR to view Datasheet
Catalog # MBS9223515
Unit / Price
  0.1 mg  /  $155 +1 FREE 8GB USB
PGLYRP4 blocking peptide
Product Name

PGLYRP4, Blocking Peptide

Popular Item
Also Known As

PGLYRP4 Antibody (Center) Blocking Peptide

Product Synonym Names
Peptidoglycan recognition protein 4; Peptidoglycan recognition protein I-beta; PGLYRPIbeta; PGRP-I-beta; Peptidoglycan recognition protein intermediate beta; PGLYRP4; PGRPIB
Product Synonym Gene Name
Antibody/Peptide Pairs
PGLYRP4 peptide (MBS9223515) is used for blocking the activity of PGLYRP4 antibody (MBS9204259)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Length
373
OMIM
608198
3D Structure
ModBase 3D Structure for Q96LB8
Clone Number
110811165
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Cellular Location
Secreted.
Tissue Location
Detected in skin epidermis, eccrine sweat glands and ducts, mucous cells in the submandibular salivary gland, mucous cells in the throat, ciliary body epithelial cells of the eye, small intestine, colon, stomach and in mature epithelial cells of the tongue (at protein level). High expression in skin and esophagus. Expressed also to a much lesser extent in the tonsils and thymus.
Preparation and Storage
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20 degree C.
Other Notes
Small volumes of PGLYRP4 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
PGLYRP4 blocking peptide
Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram- negative bacteria, and has bacteriostatic activity towards Gram- negative bacteria. Plays a role in innate immunity.
NCBI/Uniprot data below describe general gene information for PGLYRP4. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Peptidoglycan recognition protein 4
NCBI Official Synonym Full Names
peptidoglycan recognition protein 4
NCBI Official Symbol
PGLYRP4  [Similar Products]
NCBI Official Synonym Symbols
PGRPIB; SBBI67; PGRP-Ibeta; PGLYRPIbeta
  [Similar Products]
NCBI Protein Information
peptidoglycan recognition protein 4
UniProt Protein Name
Peptidoglycan recognition protein 4
UniProt Synonym Protein Names
Peptidoglycan recognition protein I-beta; PGLYRPIbeta; PGRP-I-beta; Peptidoglycan recognition protein intermediate beta
UniProt Gene Name
PGLYRP4  [Similar Products]
UniProt Synonym Gene Names
PGRPIB; PGLYRPIbeta; PGRP-I-beta  [Similar Products]
UniProt Entry Name
PGRP4_HUMAN
NCBI Summary for PGLYRP4
Summary: This gene encodes a peptidoglycan recognition protein, which belongs to the N-acetylmuramoyl-L-alanine amidase 2 family. These proteins are part of the innate immune system and recognize peptidoglycan, a ubiquitous component of bacterial cell walls. This antimicrobial protein binds to murein peptidoglycans of Gram-positive bacteria. [provided by RefSeq, Oct 2014]
UniProt Comments for PGLYRP4
PGLYRP4: Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram- negative bacteria, and has bacteriostatic activity towards Gram- negative bacteria. Plays a role in innate immunity. Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 1q21

Molecular Function: peptidoglycan binding; peptidoglycan receptor activity

Biological Process: defense response to Gram-positive bacterium; detection of bacterium
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000