• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

PHPT1 recombinant protein :: Phosphohistidine Phosphatase 1 Recombinant Protein

Scan QR to view Datasheet
Catalog # MBS144317
Unit / Price
  0.005 mg  /  $140 +1 FREE 8GB USB
  0.025 mg  /  $205 +1 FREE 8GB USB
  1 mg  /  $2,665 +3 FREE 8GB USB
PHPT1 recombinant protein
Product Name

Phosphohistidine Phosphatase 1 (PHPT1), Recombinant Protein

Popular Item
Also Known As

Recombinant Human Phosphohistidine Phosphatase 1

Product Synonym Names
PHPT1 Human; Phosphohistidine Phosphatase 1 Human Recombinant; PHP14; CGI-202; HSPC141; Phosphohistidine Phosphatase 1; Phosphohistidine Phosphatase 14kDa; Protein janus-A homolog; Sex-regulated protein Janus-a
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Length
124
Sequence
MGSSHHH HHH SSGLVPRGSH MAVADLALIP DVDIDSDGVF KYVLIRVHSA PRSGAPAAES KEIVRGYKWA EYHADIYDKV SGDMQKQGCD CECLGGGRIS HQSQDKKIHV YGYSMAYGPA QHAISTEKIK AKYPDYEVTW ANDGY
OMIM
610167
3D Structure
ModBase 3D Structure for Q9NRX4
Host
E Coli
Purity/Purification
Greater than 95% as determined by SDS-PAGE.
Form/Format
The PHPT1 protein solution (0.5mg/1ml) is formulated in 20 mM Tris-HCl buffer (pH8.0) 0.2M NaCl, 2mM DTT and 10% glycerol.
Sterile Filtered colorless solution.
Preparation and Storage
Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time.For long term storage it is recommended to add a carrier protien (0.1% HSA or BSA).Please avoid freeze thaw cycles.
Other Notes
Small volumes of PHPT1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
PHPT1 recombinant protein
Description: PHPT1 produced in E Coli is a single, non-glycosylated polypeptide chain containing 145 amino acids (1-125a.a.) and having a molecular mass of 15.9kDa.PHPT1 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

Introduction: PHPT1 is a member of the Janus protein familyand is 125 amino acid long. PHPT1 appears as a monomer in the cytoplasm and is an EDTA-insensitive phosphohistidine phosphatase. Overexpression of PHPT1 resolts in specific phosphohistidine phosphatase activity towards phosphopeptide I, with no activity detected towards phosphotyrosine, phosphothreonine and phosphoserine peptides.
NCBI/Uniprot data below describe general gene information for PHPT1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
13,672 Da
NCBI Official Full Name
14 kDa phosphohistidine phosphatase isoform 2
NCBI Official Synonym Full Names
phosphohistidine phosphatase 1
NCBI Official Symbol
PHPT1  [Similar Products]
NCBI Official Synonym Symbols
PHP14; CGI-202; HSPC141; HEL-S-132P
  [Similar Products]
NCBI Protein Information
14 kDa phosphohistidine phosphatase; epididymis secretory sperm binding protein Li 132P; protein janus-A homolog; sex-regulated protein janus-a
UniProt Protein Name
14 kDa phosphohistidine phosphatase
UniProt Synonym Protein Names
Phosphohistidine phosphatase 1; Protein janus-A homolog
UniProt Gene Name
PHPT1  [Similar Products]
UniProt Synonym Gene Names
PHP14  [Similar Products]
UniProt Entry Name
PHP14_HUMAN
NCBI Summary for PHPT1
This gene encodes an enzyme that catalyzes the reversible dephosphorylation of histidine residues in proteins. It may be involved in the dephosphorylation of G-beta and ATP citrate lyase and in negatively regulating CD4 T lymphocytes by dephosphorylation and inhibition of KCa3.1 channels. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]
UniProt Comments for PHPT1
PHPT1: a phosphohistidine phosphatase. Present preferentially in heart and skeletal muscle. Insensitive to inhibition by okadaic acid and EDTA.

Protein type: Motility/polarity/chemotaxis; Cofactor and Vitamin Metabolism - thiamine; EC 3.1.3.-; Carbohydrate Metabolism - fructose and mannose; Phosphatase; Cofactor and Vitamin Metabolism - riboflavin

Chromosomal Location of Human Ortholog: 9q34.3

Cellular Component: cytosol

Molecular Function: phosphohistidine phosphatase activity; calcium channel inhibitor activity; phosphoprotein phosphatase activity

Biological Process: negative regulation of lyase activity; negative regulation of T cell receptor signaling pathway; protein amino acid dephosphorylation
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Products associated withPHPT1 recombinant protein
 Reference Product  PubMed Publications
 KCNN4 recombinant protein  >2 publications with PHPT1 and KCNN4
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000