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anti-PKC-beta II antibody :: anti-Rat PKC-beta II Antibody

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Catalog # MBS480064
Unit / Price
  0.1 mL  /  $250 +1 FREE 8GB USB
anti-PKC-beta II antibody
Product Name

PKC-beta II, Antibody

Also Known As

Anti-Rat PKC-beta II

Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
3D Structure
ModBase 3D Structure for P05771
Species Reactivity
Preparation and Storage
At -70 degree C
Other Notes
Small volumes of anti-PKC-beta II antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for PKC-beta II. It may not necessarily be applicable to this product.
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
77,012 Da
NCBI Official Full Name
Protein kinase C beta type
NCBI Official Synonym Full Names
protein kinase C, beta
NCBI Official Symbol
PRKCB  [Similar Products]
NCBI Official Synonym Symbols
  [Similar Products]
NCBI Protein Information
protein kinase C beta type; PKC-B; protein kinase C, beta 1 polypeptide
UniProt Protein Name
Protein kinase C beta type
UniProt Gene Name
PRKCB  [Similar Products]
UniProt Synonym Gene Names
PKCB; PRKCB1; PKC-B; PKC-beta  [Similar Products]
UniProt Entry Name
NCBI Summary for PKC-beta II
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This protein kinase has been reported to be involved in many different cellular functions, such as B cell activation, apoptosis induction, endothelial cell proliferation, and intestinal sugar absorption. Studies in mice also suggest that this kinase may also regulate neuronal functions and correlate fear-induced conflict behavior after stress. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
UniProt Comments for PKC-beta II
PKCB: an AGC kinase of the PKC family. A classical PKC downstream of many mitogenic receptors. Activates the NF-kappaB signaling pathway in B cells after antigen-receptor signaling. Two splice-variant isoforms have been described.

Protein type: Protein kinase, AGC; Protein kinase, Ser/Thr (non-receptor); Motility/polarity/chemotaxis; EC; Kinase, protein; AGC group; PKC family; Alpha subfamily

Chromosomal Location of Human Ortholog: 16p11.2

Cellular Component: nucleoplasm; membrane; cytoplasm; plasma membrane; nucleus; cytosol

Molecular Function: protein serine/threonine kinase activity; protein binding; protein kinase C activity; androgen receptor binding; protein kinase C binding; ligand-dependent nuclear receptor transcription coactivator activity; zinc ion binding; histone binding; calcium channel regulator activity; chromatin binding; ATP binding

Biological Process: platelet activation; positive regulation of I-kappaB kinase/NF-kappaB cascade; B cell activation; transcription, DNA-dependent; apoptosis; positive regulation of B cell receptor signaling pathway; mitotic nuclear envelope disassembly; negative regulation of insulin receptor signaling pathway; signal transduction; protein amino acid phosphorylation; positive regulation of vascular endothelial growth factor receptor signaling pathway; activation of NF-kappaB transcription factor; regulation of transcription from RNA polymerase II promoter; cellular calcium ion homeostasis; synaptic transmission; B cell receptor signaling pathway; positive regulation of angiogenesis; lipoprotein transport; calcium ion transport; response to hypoxia; mitotic cell cycle; vascular endothelial growth factor receptor signaling pathway; blood coagulation
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While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

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