AAB60859.1
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
104,296 Da
NCBI Official Full Name
diacylglycerol kinase zeta
NCBI Official Synonym Full Names
diacylglycerol kinase zeta
NCBI Official Synonym Symbols
DAGK5; DAGK6; DGK-ZETA; hDGKzeta [Similar Products]
NCBI Protein Information
diacylglycerol kinase zeta
UniProt Protein Name
Diacylglycerol kinase zeta
UniProt Synonym Protein Names
Diglyceride kinase zeta; DGK-zeta
UniProt Synonym Gene Names
UniProt Entry Name
DGKZ_HUMAN
NCBI Summary for DGKZ
The protein encoded by this gene belongs to the eukaryotic diacylglycerol kinase family. It may attenuate protein kinase C activity by regulating diacylglycerol levels in intracellular signaling cascade and signal transduction. Alternative splicing occurs at this locus and multiple transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Nov 2010]
UniProt Comments for DGKZ
DGKZ: Displays a strong preference for 1,2-diacylglycerols over 1,3-diacylglycerols, but lacks substrate specificity among molecular species of long chain diacylglycerols. Isoform 2 but not isoform 1 regulates RASGRP1 activity. Belongs to the eukaryotic diacylglycerol kinase family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Lipid Metabolism - glycerophospholipid; Motility/polarity/chemotaxis; EC 2.7.1.107; Kinase, lipid; Lipid Metabolism - glycerolipid
Chromosomal Location of Human Ortholog: 11p11.2
Cellular Component: lamellipodium; nucleoplasm; nucleus; plasma membrane
Molecular Function: diacylglycerol kinase activity; protein binding
Biological Process: platelet activation
Research Articles on DGKZ
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Pathways associated with DGKZ elisa kit
Diseases associated with DGKZ elisa kit
Organs/Tissues associated with DGKZ elisa kit
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