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anti-PLCB2 antibody :: PLCB2 Antibody

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Catalog # MBS853325
Unit / Price
  0.1 mg  /  $215 +1 FREE 8GB USB
Western Blot
Product Name

PLCB2, Antibody

Popular Item
Also Known As

PLCB2 Antibody

Product Synonym Names
1-phosphatidylinositol-4, 5-bisphosphate phosphodiesterase beta-2; FLJ38135; Phosphoinositide phospholipase C-beta-2; phospholipase C, beta 2; Phospholipase C-beta-2; PLC-beta-2; PLCB2
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
1181
OMIM
604114
3D Structure
ModBase 3D Structure for Q00722
Species Reactivity
Human, Mouse, Rat
Specificity
PLCB2 antibody detects endogenous levels of total PLCB2 protein.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen
The antiserum was produced against synthesized peptide derived from C-terminal of human PLCB2.
Preparation and Storage
Store at-20 degree C for 1 year.
Other Notes
Small volumes of anti-PLCB2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-PLCB2 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-PLCB2 antibody
WB: 1:500~1:1000
ELISA: 1:5000

Western Blot of anti-PLCB2 antibody
Western blot analysis of extracts from K562 cells, using PLCB2 antibody.
anti-PLCB2 antibody Western Blot (WB) image
NCBI/Uniprot data below describe general gene information for PLCB2. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
132,511 Da
NCBI Official Full Name
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 isoform 2
NCBI Official Synonym Full Names
phospholipase C beta 2
NCBI Official Symbol
PLCB2  [Similar Products]
NCBI Official Synonym Symbols
PLC-beta-2
  [Similar Products]
NCBI Protein Information
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2
UniProt Protein Name
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2
UniProt Synonym Protein Names
Phosphoinositide phospholipase C-beta-2; Phospholipase C-beta-2; PLC-beta-2
UniProt Gene Name
PLCB2  [Similar Products]
UniProt Synonym Gene Names
PLC-beta-2  [Similar Products]
NCBI Summary for PLCB2
The protein encoded by this gene is a phosphodiesterase that catalyzes the hydrolysis of phosphatidylinositol 4,5-bisphosphate to the second messengers inositol 1,4,5-trisphosphate (IP3) and diacylglycerol. The encoded protein is activated by G proteins and has been shown to be involved in the type 2 taste receptor signal transduction pathway. In addition, nuclear factor kappa B can regulate the transcription of this gene, whose protein product is also an important regulator of platelet responses. [provided by RefSeq, Jan 2017]
UniProt Comments for PLCB2
The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.
Product References and Citations for anti-PLCB2 antibody
Park D., J. Biol. Chem. 267:16048-16055(1992). Ota T., Nat. Genet. 36:40-45(2004). Zody M.C., Nature 440:671-675(2006).

Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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