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PLDN peptide :: Pallidin Peptide

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Catalog # MBS425308
Unit / Price
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  0.1 mg  /  $190 +1 FREE 8GB USB
PLDN peptide
Product Name

Pallidin (PLDN), Peptide

Full Product Name

Pallidin Immunizing Peptide

Product Synonym Names
pallidin homolog (mouse); pallidin; PLDN; PA; PALLID; pallid (mouse) homolog, pallidin; syntaxin 13 binding protein 1; syntaxin 13-interacting protein pallid; Pallidin; Pallidin
Product Gene Name
Antibody/Peptide Pairs
Pallidin peptide (MBS425308) is used for blocking the activity of Pallidin antibody (MBS421440)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
C-EREKQLTA RPAKRM
OMIM
604310
Species Reactivity
Human, Mouse, Rat, Pig, Cow
Form/Format
100ug of dried peptide
Preparation and Storage
Shipped at ambient temperature, store at -20 degree C
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Other Notes
Small volumes of PLDN peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for PLDN. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Related Accession #
Molecular Weight
– Da
NCBI Official Full Name
biogenesis of lysosome-related organelles complex 1 subunit 6 isoform 2
NCBI Official Synonym Full Names
biogenesis of lysosomal organelles complex 1 subunit 6
NCBI Official Symbol
BLOC1S6  [Similar Products]
NCBI Official Synonym Symbols
PA; HPS9; PLDN; BLOS6; PALLID
  [Similar Products]
NCBI Protein Information
biogenesis of lysosome-related organelles complex 1 subunit 6
UniProt Protein Name
Biogenesis of lysosome-related organelles complex 1 subunit 6
UniProt Synonym Protein Names
Pallid protein homolog; Pallidin; Syntaxin 13-interacting protein
UniProt Gene Name
BLOC1S6  [Similar Products]
UniProt Synonym Gene Names
PA; PLDN; BLOC-1 subunit 6  [Similar Products]
UniProt Entry Name
BL1S6_HUMAN
NCBI Summary for PLDN
The protein encoded by this gene may play a role in intracellular vesicle trafficking. It interacts with Syntaxin 13 which mediates intracellular membrane fusion. Mutations in this gene cause symptoms associated with Hermansky-Pudlak syndrome-9. Alternative splicing results in multiple transcript variants. A pseudogene related to this gene is located on the X chromosome. [provided by RefSeq, Aug 2015]
UniProt Comments for PLDN
PLDN: Involved in the development of lysosome-related organelles, such as melanosomes and platelet-dense granules. May play a role in intracellular vesicle trafficking, particularly in the vesicle-docking and fusion process. Defects in PLDN are the cause of Hermansky-Pudlak syndrome type 9 (HPS9). A form of Hermansky-Pudlak syndrome, a genetically heterogeneous autosomal recessive disorder characterized by oculocutaneous albinism, bleeding due to platelet storage pool deficiency, and lysosomal storage defects. This syndrome results from defects of diverse cytoplasmic organelles including melanosomes, platelet dense granules and lysosomes. Ceroid storage in the lungs is associated with pulmonary fibrosis, a common cause of premature death in individuals with HPS. 3 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 15q21.1

Cellular Component: cytoplasm; cytosol; endosome; extrinsic to membrane; nucleoplasm; SNARE complex; transport vesicle

Molecular Function: actin filament binding; identical protein binding; protein binding; protein homodimerization activity; syntaxin binding

Biological Process: anterograde axon cargo transport; anterograde synaptic vesicle transport; blood coagulation; melanocyte differentiation; melanosome organization and biogenesis; melanosome transport; neurite development; positive regulation of natural killer cell activation; positive regulation of pigment cell differentiation; secretion of lysosomal enzymes; synaptic vesicle docking during exocytosis

Disease: Hermansky-pudlak Syndrome 9
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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