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Pnpla2 elisa kit :: Mouse Patatin-like phospholipase domain-containing protein 2 ELISA Kit

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Catalog # MBS2881428
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  48-Strip-Wells  /  $400 +1 FREE 8GB USB
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Pnpla2 elisa kit
Product Name

Patatin-like phospholipase domain-containing protein 2 (Pnpla2), ELISA Kit

Popular Item
Full Product Name

Mouse Patatin-like phospholipase domain-containing protein 2 ELISA Kit

Product Synonym Names
Patatin-like phospholipase domain-containing protein 2; Adipose triglyceride lipase; Desnutrin; Pnpla2; Atgl; 3.1.1.3
Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Request for Current Manual Insert
3D Structure
ModBase 3D Structure for Q8BJ56
Species Reactivity
Assay Type
Sandwich
Detection Range
0.156-10 ng/ml
Sensitivity
0.086 ng/mL
Intra-Assay CV
<=4.8%
Inter-Assay CV
<=7.5%
Recovery
92%
Preparation and Storage
For long term storage, please store the entire kit at -20 degree C.
Product Note
Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
Other Notes
Small volumes of Pnpla2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms forPnpla2purchase
MBS2881428 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Patatin-like phospholipase domain-containing protein 2 (Pnpla2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing Pnpla2. The ELISA analytical biochemical technique of the MBS2881428 kit is based on Pnpla2 antibody-Pnpla2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect Pnpla2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, Pnpla2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
NCBI/Uniprot data below describe general gene information for Pnpla2. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
47,877 Da
NCBI Official Full Name
patatin-like phospholipase domain-containing protein 2 isoform 1
NCBI Official Synonym Full Names
patatin-like phospholipase domain containing 2
NCBI Official Symbol
Pnpla2  [Similar Products]
NCBI Official Synonym Symbols
Atgl; TTS-2.2; 0610039C21Rik; 1110001C14Rik
  [Similar Products]
NCBI Protein Information
patatin-like phospholipase domain-containing protein 2
UniProt Protein Name
Patatin-like phospholipase domain-containing protein 2
UniProt Synonym Protein Names
Adipose triglyceride lipase; Desnutrin
UniProt Gene Name
Pnpla2  [Similar Products]
UniProt Synonym Gene Names
UniProt Entry Name
PLPL2_MOUSE
UniProt Comments for Pnpla2
PNPLA2: the rate-limiting lipolytic enzyme in mammals, flies, and yeast. Catalyzes the initial step in triglyceride hydrolysis in adipocyte and non-adipocyte lipid droplets. Upregulated by exercise training in human skeletal muscle. Has acylglycerol transacylase activity. May act coordinately with HSL within the lipolytic cascade. Regulates adiposome size and may be involved in the degradation of adiposomes. May play an important role in energy homeostasis. May play a role in the response of the organism to starvation, enhancing hydrolysis of triglycerides and providing free fatty acids to other tissues to be oxidized in situations of energy depletion. Interacting with ABHD5 stimulates its triglyceride hydrolase activity. Despite a colocalization in lipid droplets, it probably does not interact with perilipin. Transcriptionally regulated by FOXO1A. Defects cause neutral lipid storage disease (NLSD), an autosomal recessive disorder characterized by the excessive accumulation of neutral lipids in multiple tissues. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.1.1.3; Lipase; Membrane protein, integral

Cellular Component: cytosol; integral to membrane; lipid particle; membrane; plasma membrane

Molecular Function: hydrolase activity; protein binding; triacylglycerol lipase activity

Biological Process: lipid catabolic process; lipid metabolic process; metabolic process; sequestering of lipid; triacylglycerol catabolic process
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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