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PNPLA8 cdna clone

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Catalog # MBS1277307
Unit / Price
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  0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $390 +1 FREE 8GB USB
PNPLA8 cdna clone
Product Name

PNPLA8, cDNA Clone

Full Product Name

PNPLA8 cDNA Clone

Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
atgtctatta atctgactgt agatatatat atttacctcc ttagtaatgc aagaagtgtt tgtgggaagc agagaagcaa gcaactgtat ttcttgttct cacctaagca ttactggagg ataagccaca tcagtctaca aagaggtttt catacaaaca taataagatg taaatggacc aaaagtgaag cacattcttg cagtaagcac tgttactctc caagcaacca tggtttacat attgggattt tgaaacttag cacttctgct cccaagggac ttacaaaagt gaacatttgt atgtcccgta ttaaaagtac tttgaactct gtttcaaagg ctgtttttgg caatcaaaat gaaatgattt cacgtttagc tcaatttaag ccaagttccc aaattttaag aaaagtatcg gatagtggct ggttaaaaca gaaaaacatc aaacaagcca tcaaatctct gaaaaaatat agtgacaaat cagcagaaaa gagtcctttt ccagaagaga aaagtcacat tatagacaaa gaagaagata taggtaaacg cagtcttttt cattacacaa gttctataac cacaaaattt ggagactcat tctacttttt atcaaatcat attaattcat atttcaaacg taaggaaaaa atgtctcaac aaaaggaaaa tgaacatttc cgggacaaat cagaacttga agataaaaag gtagaagagg ggaaattaag atctccagat cctggcatcc tggcttataa gccaggctca gaatctgtac atacggtgga caagcctaca agtccttctg cgatacctga tgttcttcaa gtttcaacta aacaaagtat tgctaacttt ctttctcgtc ccacggaagg tgtacaagct ttagtaggtg gttatattgg tggacttgtc cccaaattaa agtatgattc aaagagtcag tcagaagaac aggaagagcc tgctaaaact gatcaggctg tcagcaaaga cagaaatgca gaggagaaaa agcgtttatc tcttcagcga gaaaagatta tcgcaagggt gagtattgat aacaggaccc gggcattagt tcaggcatta agaagaacaa ctgacccaaa gctctgcatt actagggttg aagaactgac ttttcatctt ctagaatttc ctgaaggaaa aggagtggct gtcaaggaaa gaattattcc atatttatta cgactgagac aaattaagga tgaaactctt caggctgcag ttagagaaat tttggcccta attggctatg tggatccagt gaaagggaga ggaatccgaa ttctctcaat tgatggtgga ggaacaaggg gcgtggttgc tctccagacc ctacgaaaat tagttgaact tactcagaag ccagttcatc agctctttga ttacatttgt ggtgtaagca caggtgccat attagctttc atgttggggt tgtttcatat gcccttggat gaatgtgagg aactttatcg aaaattagga tcagatgtat tttcacaaaa tgtcattgtt ggaacagtaa aaatgagttg gagccatgca ttttatgaca gtcaaacatg ggaaaacatt cttaaggata ggatgggatc tgcactgatg attgaaacag caagaaaccc cacatgtcct aaggtagctg ctgtaagtac catagtaaat agagggataa cacccaaagc ttttgtgttc agaaactatg gtcattttcc tggaatcaac tctcattatt tgggaggctg tcagtataaa atgtggcagg ccattagagc ctcatctgct gctccaggct actttgcaga atatgcattg ggaaatgatc ttcatcaaga tggaggtttg cttctgaata acccttcggc attagctatg catgagtgta aatgtctttg gccagatgtg ccgttagagt gcatagtatc cctgggcact ggacgttatg agagtgatgt gagaaacacg gtaacataca caagcttgaa aactaaactt tctaatgtta tcaacagtgc tacagataca gaagaagtcc atataatgct tgatggcctg ttacctcctg acacctattt tagattcaat cctgtaatgt gtgaaaacat acctctagat gaaagtcgaa atgaaaagct ggatcagctg cagttggaag ggttgaaata catagaaaga aatgaacaaa aaatgaaaaa agttgcaaaa atattaagtc aagaaaaaac aactctgcag aaaattaatg attggataaa attaaaaact gatatgtatg aaggacttcc attcttttca aaattgtga
OMIM
251950
Vector
pENTR223.1 or pUC
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of PNPLA8 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for PNPLA8. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
77,031 Da
NCBI Official Full Name
Homo sapiens patatin-like phospholipase domain containing 8, mRNA
NCBI Official Synonym Full Names
patatin like phospholipase domain containing 8
NCBI Official Symbol
PNPLA8  [Similar Products]
NCBI Official Synonym Symbols
MMLA; IPLA2G; IPLA2-2; iPLA2gamma; PNPLA-gamma
  [Similar Products]
NCBI Protein Information
calcium-independent phospholipase A2-gamma
UniProt Protein Name
Calcium-independent phospholipase A2-gamma
UniProt Synonym Protein Names
Intracellular membrane-associated calcium-independent phospholipase A2 gamma; iPLA2-gamma; PNPLA-gamma; Patatin-like phospholipase domain-containing protein 8; iPLA2-2
UniProt Gene Name
PNPLA8  [Similar Products]
UniProt Synonym Gene Names
IPLA22; IPLA2G; iPLA2-gamma  [Similar Products]
UniProt Entry Name
PLPL8_HUMAN
NCBI Summary for PNPLA8
This gene encodes a member of the patatin-like phospholipase domain containing protein family. Members of this family are phospholipases which catalyze the cleavage of fatty acids from membrane phospholipids. The product of this gene is a calcium-independent phospholipase. Mutations in this gene have been associated with mitochondrial myopathy with lactic acidosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2015]
UniProt Comments for PNPLA8
PNPLA8: Calcium-independent phospholipase A2, which catalyzes the hydrolysis of the sn-2 position of glycerophospholipids, PtdSer and to a lower extent PtdCho. Cleaves membrane phospholipids. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Phospholipase; Membrane protein, integral; Motility/polarity/chemotaxis; EC 3.1.1.5

Chromosomal Location of Human Ortholog: 7q31

Cellular Component: endoplasmic reticulum membrane; intracellular; membrane; peroxisomal membrane; peroxisome

Molecular Function: calcium-independent phospholipase A2 activity; phospholipase A2 activity

Biological Process: arachidonic acid metabolic process; arachidonic acid secretion; cell death; fatty acid metabolic process; linoleic acid metabolic process; phosphatidylethanolamine catabolic process; prostaglandin biosynthetic process

Disease: Mitochondrial Myopathy With Lactic Acidosis
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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