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POLR2K cdna clone

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Catalog # MBS1271511
Unit / Price
  0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $165 +1 FREE 8GB USB
POLR2K cdna clone
Product Name

POLR2K, cDNA Clone

Popular Item
Full Product Name

POLR2K cDNA Clone

Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
atggacaccc agaaggacgt tcaacctcca aagcagcaac caatgatata tatctgtgga gagtgtcaca cagaaaatga aataaaatct agggatccaa tcagatgcag agaatgtgga tacagaataa tgtacaagaa aaggactaaa agattggtcg tttttgatgc tcgatga
OMIM
606033
Vector
pENTR223.1
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of POLR2K cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for POLR2K. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
7,004 Da
NCBI Official Full Name
Homo sapiens polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa, mRNA
NCBI Official Synonym Full Names
RNA polymerase II subunit K
NCBI Official Symbol
POLR2K  [Similar Products]
NCBI Official Synonym Symbols
RPB12; RPABC4; RPB7.0; hRPB7.0; hsRPB10a; RPB10alpha; ABC10-alpha
  [Similar Products]
NCBI Protein Information
DNA-directed RNA polymerases I, II, and III subunit RPABC4
UniProt Protein Name
DNA-directed RNA polymerases I, II, and III subunit RPABC4
UniProt Synonym Protein Names
ABC10-alpha; DNA-directed RNA polymerase II subunit K; RNA polymerase II 7.0 kDa subunit; RPB7.0; RPB10alpha
UniProt Gene Name
POLR2K  [Similar Products]
UniProt Synonym Gene Names
RNA polymerases I, II, and III subunit ABC4; RPB7.0  [Similar Products]
UniProt Entry Name
RPAB4_HUMAN
NCBI Summary for POLR2K
This gene encodes one of the smallest subunits of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This subunit is shared by the other two DNA-directed RNA polymerases. [provided by RefSeq, Jul 2008]
UniProt Comments for POLR2K
POLR2K: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and a small RNAs, such as 5S rRNA and tRNAs, respectively. Belongs to the archaeal RpoP/eukaryotic RPC10 RNA polymerase subunit family.

Protein type: DNA repair, damage; RNA processing

Chromosomal Location of Human Ortholog: 8q22.2

Cellular Component: cytosol; DNA-directed RNA polymerase I complex; DNA-directed RNA polymerase II, core complex; DNA-directed RNA polymerase III complex; nucleoplasm; nucleus

Molecular Function: zinc ion binding

Biological Process: fibroblast growth factor receptor signaling pathway; gene expression; mRNA capping; nuclear mRNA splicing, via spliceosome; positive regulation of gene expression, epigenetic; positive regulation of interferon type I production; positive regulation of viral transcription; regulation of transcription from RNA polymerase I promoter; RNA elongation from RNA polymerase I promoter; RNA elongation from RNA polymerase II promoter; RNA-mediated gene silencing; snRNA transcription from RNA polymerase II promoter; somatic stem cell maintenance; termination of RNA polymerase I transcription; transcription from RNA polymerase II promoter; transcription from RNA polymerase III promoter; transcription initiation from RNA polymerase I promoter; transcription initiation from RNA polymerase II promoter; transcription-coupled nucleotide-excision repair
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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