P33765.2
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Synonym Full Names
adenosine A3 receptor
NCBI Official Synonym Symbols
NCBI Protein Information
adenosine receptor A3
UniProt Protein Name
Adenosine receptor A3
NCBI Summary for ADORA3
This gene encodes a protein that belongs to the family of adenosine receptors, which are G-protein-coupled receptors that are involved in a variety of intracellular signaling pathways and physiological functions. The receptor encoded by this gene mediates a sustained cardioprotective function during cardiac ischemia, it is involved in the inhibition of neutrophil degranulation in neutrophil-mediated tissue injury, it has been implicated in both neuroprotective and neurodegenerative effects, and it may also mediate both cell proliferation and cell death. Alternative splicing results in multiple transcript variants. This gene shares its 5' terminal exon with some transcripts from overlapping GeneID:57413, which encodes an immunoglobulin domain-containing protein. [provided by RefSeq, Nov 2014]
UniProt Comments for ADORA3
Isoform 2: Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibits adenylyl cyclase (PubMed:8234299).
Research Articles on ADORA3
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Products associated with anti-ADORA3 antibody
Pathways associated with anti-ADORA3 antibody
Diseases associated with anti-ADORA3 antibody
Organs/Tissues associated with anti-ADORA3 antibody
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