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anti-AMBP antibody :: Sheep ALPHA 1 MICROGLOBULIN Polyclonal Antibody

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Catalog # MBS224210
Unit / Price
  1 mL  /  $370 +1 FREE 8GB USB
Testing Data #1
Product Name

ALPHA 1 MICROGLOBULIN (AMBP), Polyclonal Antibody

Also Known As

SHEEP ANTI HUMAN ALPHA 1 MICROGLOBULIN

Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
352
OMIM
176870
3D Structure
ModBase 3D Structure for P02760
Clonality
Polyclonal
Isotype
IgG
Host
Sheep
Specificity
This item recognises human alpha 1 microglobulin.
Form/Format
Serum
Serum - liquid
Perservative Stabilisers
0.09% Sodium Azide (NaN3)
Immunogen
Native, purified alpha-1-microglobulin prepared from human urine.
Antiserum Preparation
Antiserum to human alpha 1 microglobulin was raised by repeated immunisation of sheep with highly purified antigen.
Target Species
Human
Preparation and Storage
Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.
Other Notes
Small volumes of anti-AMBP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-AMBP antibody
MBS224210 recognises human alpha 1 microglobulin.
Applications Tested/Suitable for anti-AMBP antibody
ELISA (EIA)

Testing Data #1 of anti-AMBP antibody
Alpha 1 Microglobulin detected with Sheep anti Alpha 1 Microglobulin (MBS224210) followed by Donkey anti Sheep/Goat IgG:HRP (MBS235204)
anti-AMBP antibody Testing Data #1 image
NCBI/Uniprot data below describe general gene information for AMBP. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
38,999 Da[Similar Products]
NCBI Official Full Name
protein AMBP preproprotein
NCBI Official Synonym Full Names
alpha-1-microglobulin/bikunin precursor
NCBI Official Symbol
NCBI Official Synonym Symbols
A1M; HCP; ITI; UTI; EDC1; HI30; ITIL; IATIL; ITILC
  [Similar Products]
NCBI Protein Information
protein AMBP; bikunin; complex-forming glycoprotein heterogeneous in charge; growth-inhibiting protein 19; inter-alpha-trypsin inhibitor light chain; protein HC; trypstatin; uristatin; uronic-acid-rich protein
UniProt Protein Name
Protein AMBP
UniProt Synonym Protein Names
Alpha-1 microglycoprotein; Complex-forming glycoprotein heterogeneous in charge
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
HCP; ITIL; Protein HC; ITI-LC  [Similar Products]
UniProt Entry Name
AMBP_HUMAN
NCBI Summary for AMBP
This gene encodes a complex glycoprotein secreted in plasma. The precursor is proteolytically processed into distinct functioning proteins: alpha-1-microglobulin, which belongs to the superfamily of lipocalin transport proteins and may play a role in the regulation of inflammatory processes, and bikunin, which is a urinary trypsin inhibitor belonging to the superfamily of Kunitz-type protease inhibitors and plays an important role in many physiological and pathological processes. This gene is located on chromosome 9 in a cluster of lipocalin genes. [provided by RefSeq, Jul 2008]
UniProt Comments for AMBP
AMBP: Inter-alpha-trypsin inhibitor inhibits trypsin, plasmin, and lysosomal granulocytic elastase. Inhibits calcium oxalate crystallization.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 9q32-q33

Cellular Component: extracellular space; cell surface; intracellular membrane-bound organelle; plasma membrane; extracellular region

Molecular Function: serine-type endopeptidase inhibitor activity; protein binding; protein homodimerization activity; calcium oxalate binding; heme binding; IgA binding; calcium channel inhibitor activity

Biological Process: receptor-mediated endocytosis; negative regulation of JNK cascade; viral reproduction; heme catabolic process; negative regulation of immune response; protein catabolic process; female pregnancy; cell adhesion; protein-chromophore linkage
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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