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anti-APOA2 antibody :: Sheep Apolipoprotein (a) (Apo (a)) Polyclonal Antibody

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Catalog # MBS316055
Unit / Price
  1 mg  /  $575 +1 FREE 8GB USB
anti-APOA2 antibody
Product Name

Apolipoprotein (a) (Apo (a)) (APOA2), Polyclonal Antibody

Popular Item
Also Known As

Sheep anti Human Apolipoprotein (a)

Product Synonym Names
Sheep Antibody to Human Apolipoprotein (a), (Apo (a))
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
100
Chromosome Location
Chromosome: 1; NC_000001.10 (161192083..161193418, complement). Location: 1q21-q23
OMIM
107670
3D Structure
ModBase 3D Structure for P02652
Clonality
Polyclonal
Host
Sheep
Specificity
Apolipoprotein (a) (Apo (a))
Specifically binds to human Lp(a) and Apo(a).
Purity/Purification
Human Apo (a) Sepharose affinity column. Cross-reactivity to plasminogen was removed by passing plasminogen-Sepharose affinity column.
Form/Format
Affinity Purified, Liquid
Concentration
1mg/ml (OD280nm, E^0.1% = 1.35) (lot specific)
Buffer
50mM Sodium borate, 0.15M Sodium chloride, 0.5mM EDTA, pH 7.2
Preservative
0.02% Sodium azide
Important Note
Centrifuge before opening to ensure complete recovery of vial contents.
Warnings
This product contains sodium azide, which has been classified as Xn (Harmful) in European Directive 67/548/EEC in the concentration range of 0.1 - 1.0 %. When disposing of this reagent through lead or copper plumbing, flush with copious volumes of water to prevent azide build-up in drains.
Preparation and Storage
Short-term store at 2 to 8 degree C. Long term store at -20 degree C. Avoid multiple freeze/thaw cycles.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-APOA2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-APOA2 antibody
EIA/ELISA, Western Blot
NCBI/Uniprot data below describe general gene information for APOA2. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
11,175 Da[Similar Products]
NCBI Official Full Name
apolipoprotein
NCBI Official Synonym Full Names
apolipoprotein A-II
NCBI Official Symbol
APOA2  [Similar Products]
NCBI Official Synonym Symbols
apoAII; Apo-AII; ApoA-II
  [Similar Products]
NCBI Protein Information
apolipoprotein A-II; apolipoprotein A2; OTTHUMP00000032244
UniProt Protein Name
Apolipoprotein A-II
UniProt Synonym Protein Names
Apolipoprotein A2
Protein Family
UniProt Gene Name
APOA2  [Similar Products]
UniProt Entry Name
APOA2_HUMAN
NCBI Summary for APOA2
This gene encodes apolipoprotein (apo-) A-II, which is the second most abundant protein of the high density lipoprotein particles. The protein is found in plasma as a monomer, homodimer, or heterodimer with apolipoprotein D. Defects in this gene may result in apolipoprotein A-II deficiency or hypercholesterolemia. [provided by RefSeq]
UniProt Comments for APOA2
Function: May stabilize HDL (high density lipoprotein) structure by its association with lipids, and affect the HDL metabolism.

Subunit structure: Homodimer; disulfide-linked. Also forms a disulfide-linked heterodimer with APOD. Interacts with HCV core protein. Interacts with APOA1BP. Ref.14 Ref.15 Ref.18

Subcellular location: Secreted.

Tissue specificity: Plasma; synthesized in the liver and intestine.

Post-translational modification: Phosphorylation sites are present in the extracelllular medium.

Sequence similarities: Belongs to the apolipoprotein A2 family.

Mass spectrometry: Molecular mass is 8701.2 Da from positions 24 - 100. Determined by MALDI. Ref.16Molecular mass is 8823.4 Da from positions 24 - 100. Determined by MALDI. Cysteinylated ApoA-II. Ref.16Molecular mass is 17421.3 Da from positions 24 - 100. Determined by MALDI. Homodimer. Ref.16Molecular mass is 17293.4 Da from positions 24 - 100. Determined by MALDI. Heterodimer with apolipoprotein A-II(1-76). Ref.16Molecular mass is 8578.3 Da from positions 24 - 99. Determined by MALDI. Ref.16Molecular mass is 17166.2 Da from positions 24 - 99. Determined by MALDI. Homodimer. Ref.16
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Products associated withanti-APOA2 antibody
 Reference Product  PubMed Publications
 APOC1 antibody  >1 publications with APOA2 and APOC1
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