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anti-AHSG antibody :: Sheep ASIALOFETUIN Polyclonal Antibody

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Catalog # MBS220674
Unit / Price
  1 mL  /  $375 +1 FREE 8GB USB
anti-AHSG antibody
Product Name

ASIALOFETUIN (AHSG), Polyclonal Antibody

Popular Item
Full Product Name

SHEEP ANTI BOVINE ASIALOFETUIN

Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P12763
Clonality
Polyclonal
Isotype
IgG
Host
Sheep
Form/Format
Purified
Purified IgG - liquid
Concentration
IgG concentration 5.0 mg/ml (lot specific)
Perservative Stabilisers
0.09% Sodium Azide (NaN3)
Preparation
Buffer Solution
Phosphate buffered saline
Target Species
Bovine
Preparation and Storage
Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.
Other Notes
Small volumes of anti-AHSG antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-AHSG antibody
Sheep anti Bovine asialofetuin antibody recognizes bovine Alpha-2-HS-glycoprotein, also known as asialofetuin or fetuin-A. Asialofetuin is a 359 amino acid ~55kDa secreted glycoprotein containing two cystatin fetuin-A-type domains. Asialofetuin is produced in the liver and bone marrow and acts as a negative acute-phase protein attenuating the inflammatory response to acute injury (Wang et al. 2010). In a simple antigen down ELISA assay Sheep anti Bovine asialofetuin antibody reacts with: asialofetuin (ab at 1/8000) 100%fetuin (ab at 1/2000) 100%fetuin (ab at 1/8000) 50%
Applications Tested/Suitable for anti-AHSG antibody
ELISA (EIA)
Application Notes for anti-AHSG antibody
ELISA: Minimum Dilution: 1/1000; Maximum Dilution: 1/4000
NCBI/Uniprot data below describe general gene information for AHSG. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
38,419 Da[Similar Products]
NCBI Official Full Name
alpha-2-HS-glycoprotein
NCBI Official Synonym Full Names
alpha-2-HS-glycoprotein
NCBI Official Symbol
NCBI Protein Information
alpha-2-HS-glycoprotein; asialofetuin; fetuin-A
UniProt Protein Name
Alpha-2-HS-glycoprotein
UniProt Synonym Protein Names
Asialofetuin; Fetuin-A
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
FETUA  [Similar Products]
UniProt Entry Name
FETUA_BOVIN
UniProt Comments for AHSG
FETUA: Promotes endocytosis, possesses opsonic properties and influences the mineral phase of bone. Shows affinity for calcium and barium ions. Alpha-2-HS glycoprotein derives from this precursor, when the connecting peptide is cleaved off. The two chains A and B are held together by a single disulfide bond. Synthesized in liver and selectively concentrated in bone matrix. Secreted in plasma. It is also found in dentin in much higher quantities than other plasma proteins. Belongs to the fetuin family.

Protein type: Secreted; Secreted, signal peptide

Cellular Component: plasma membrane; vesicle

Molecular Function: protein binding; cysteine protease inhibitor activity

Biological Process: negative regulation of bone mineralization; ossification; positive regulation of phagocytosis; regulation of inflammatory response; acute-phase response
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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