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anti-HA antibody :: Goat anti-Virus Avian Influenza Hemagglutinin 1 Polyclonal Antibody

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Catalog # MBS151143
Unit / Price
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  0.1 mg  /  $375 +1 FREE 8GB USB
Testing Data
Product Name

Avian Influenza Hemagglutinin 1 (HA), Polyclonal Antibody

Full Product Name

Avian Influenza Hemagglutinin 1 Antibody

Product Synonym Names
Avian Influenza Hemagglutinin 1; hemagglutinin
Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q692M2
Clonality
Polyclonal
Isotype
IgG
Host
Goat
Species Reactivity
Virus
Purity/Purification
Avian Influenza Hemagglutinin 1 Antibody is affinity chromatography purified via peptide column.
Form/Format
Liquid
Concentration
1 mg/mL (lot specific)
Conjugate
Unconjugated
Immunogen
Avian Influenza Hemagglutinin 1 antibody was raised against a synthetic peptide corresponding to 14 amino acids in the middle of the Avian Influenza Hemagglutinin 1 protein. Efforts were made to use relatively conserved regions of the viral sequence as the antigen.
Buffer
Avian Influenza Hemagglutinin 1 Antibody is supplied in PBS containing 0.02% sodium azide.
Preparation and Storage
Avian Influenza Hemagglutinin 1 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Other Notes
Small volumes of anti-HA antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-HA antibody
Avian Influenza Hemagglutinin 1 Antibody: Influenza A virus is a major public health threat, killing more than 30, 000 people per year in the USA. Novel influenza virus strains caused by genetic drift and viral recombination emerge periodically to which humans have little or no immunity, resulting in devastating pandemics. Influenza A can exist in a variety of animals; however it is in birds that all subtypes can be found. These subtypes are classified based on the combination of the virus coat glycoproteins hemagglutinin (HA) and neuraminidase (NA) subtypes. During 1997, an H5N1 avian influenza virus was determined to be the cause of death in 6 of 18 infected patients in Hong Kong. There was some evidence of human to human spread of this virus, but it is thought that the transmission efficiency was fairly low. HA interacts with cell surface proteins containing oligosaccharides with terminal sialyl residues. Virus isolated from a human infected with the H5N1 strain in 1997 could bind to oligosaccharides from human as well as avian sources, indicating its species-jumping ability.
Applications Tested/Suitable for anti-HA antibody
ELISA (EIA)
Application Notes for anti-HA antibody
Avian Influenza Hemagglutinin 1 antibody can be used for the detection of the Avian Influenza Hemagglutinin 1 protein from the H5N1 strain of avian influenza A in ELISA. It will detect 10 ng of free peptide at 1 mug/mL.

Testing Data of anti-HA antibody
Hemagglutinin antibody at 1 μg/mL specifically recognizes Avian H5N1 influenza virus but not seasonal influenza virus A H1N1 Hemagglutinin protein.
anti-HA antibody Testing Data image
NCBI/Uniprot data below describe general gene information for HA. It may not necessarily be applicable to this product.
NCBI GI #
NCBI Accession #
UniProt Primary Accession #
Molecular Weight
64,262 Da
NCBI Official Full Name
hemagglutinin
UniProt Protein Name
Hemagglutinin
Protein Family
UniProt Gene Name
UniProt Entry Name
Q692M2_9INFA
UniProt Comments for HA
Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell. This attachment induces virion internalization of about two third of the virus particles through clathrin-dependent endocytosis and about one third through a clathrin- and caveolin-independent pathway. Plays a major role in the determination of host range restriction and virulence. Class I viral fusion protein. Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane. Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide. Several trimers are required to form a competent fusion pore.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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