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anti-C-JUN antibody :: Rabbit c-Jun Polyclonal Antibody

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Catalog # MBS194196
Unit / Price
  0.025 mL  /  $225 +1 FREE 8GB USB
  0.1 mg  /  $395 +1 FREE 8GB USB
anti-C-JUN antibody
Product Name

c-Jun, Polyclonal Antibody

Also Known As

c-Jun Polyclonal Antibody

Product Synonym Names
c-Jun Antibody; c-Jun
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Chromosome Location
Chromosome: 6; NC_010448.2 (141029845..141031055)
3D Structure
ModBase 3D Structure for P56432
Clonality
Polyclonal
Host
Rabbit
Specificity
c-Jun Antibody [Rabbit polyclonal antibody to c-Jun]
This antibody recognizes human, monkey, rat, mouse, hamster, rabbit, ovine, porcine, bovine, canine, chicken, guinea pig, Xenopus, and Drosophila c- Jun.
Form/Format
25 ug, Supplied as affinity purified antibody at 1 mg/ml in borate buffered saline, pH 8.4.
Antigen
Peptide corresponding to aa 266-285 of human c-Jun.
Stabilizer
None
Preservatives
0.02% Sodium Azide
Dilutions Instructions
Dilute in PBS or medium that is identical to that used in the assay system.
Preparation and Storage
Store frozen product at or below -20 degree C. Thawed product may be stored for 2-4 weeks at 4 degree C. For optimal storage, aliquot to smaller portions and store at -20 degree C to -70 degree C. Avoid repeated freeze/thaw cycles.
Other Notes
Small volumes of anti-C-JUN antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-C-JUN antibody
Western Blot, Immunoblot
Application Notes for anti-C-JUN antibody
Western Blot: Use at 1 ug/ml. A band of approximately 46 kD is detected on immunoblots and corresponds to the molecular weight of c-Jun.
NCBI/Uniprot data below describe general gene information for C-JUN. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
UniProt Primary Accession #
UniProt Related Accession #
Molecular Weight
35,629 Da[Similar Products]
NCBI Official Full Name
c-Jun
NCBI Official Symbol
C-JUN  [Similar Products]
NCBI Official Synonym Symbols
NCBI Protein Information
transcription factor AP-1; AP1; activator protein 1; proto-oncogene c-jun; V-jun avian sarcoma virus 17 oncogene homolog
UniProt Protein Name
Transcription factor AP-1
UniProt Synonym Protein Names
Activator protein 1; AP1; Proto-oncogene c-Jun; V-jun avian sarcoma virus 17 oncogene homolog
UniProt Gene Name
UniProt Entry Name
JUN_PIG
UniProt Comments for C-JUN
Function: Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'.

Subunit structure: Heterodimer with either FOS or BATF3 or ATF7

By similarity. The ATF7/JUN heterodimer is essential for ATF7 transactivation activity. Interacts with MYBBP1A, SP1, SPIB and TCF20. Interacts with COPS5; indirectly leading to its phosphorylation. Interacts with DSIPI; this interaction inhibits the binding of active AP1 to its target DNA. Interacts with HIVEP3. Component of the SMAD3/SMAD4/JUN/FOS/complex which forms at the AP1 promoter site. The SMAD3/SMAD4 heterodimer acts syngernistically with the JUN/FOS heterodimer to activate transcription in response to TGF-beta. Interacts (via its basic DNA binding and leucine zipper domains) with SMAD3 (via an N-terminal domain); the interaction is required for TGF-beta-mediated transactivation of the SMAD3/SMAD4/JUN/FOS/complex

By similarity. Interacts with RNF187

Subcellular location: Nucleus

Post-translational modification: Phosphorylation enhances the transcriptional activity. Phosphorylated by PRKDC

Sequence similarities: Belongs to the bZIP family. Jun subfamily.Contains 1 bZIP domain.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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