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anti-CRP antibody :: Goat C-REACTIVE PROTEIN Polyclonal Antibody

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Catalog # MBS224050
Unit / Price
  1 mL  /  $175 +1 FREE 8GB USB
anti-CRP antibody
Product Name

C-REACTIVE PROTEIN (CRP), Polyclonal Antibody

Also Known As

GOAT ANTI HUMAN C-REACTIVE PROTEIN

Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
224
OMIM
123260
3D Structure
ModBase 3D Structure for P02741
Clonality
Polyclonal
Isotype
IgG
Host
Goat
Specificity
This item recognizes human C-reactive protein (CRP), a calcium-binding acute phase reactant belonging to the pentraxin family which is secreted into the plasma by the liver, in response to cytokine stimulation.

Levels of plasma CRP are significantly increased during the acute phase response, tissue injury and infection and can be used diagnostically as a marker of inflammation, disease progress and risk assessment of cardiovascular disease (CVD).

This reagent is available in bulk quantities and may be made available in other formats. Please enquire for further details.
Form/Format
Serum
Serum - liquid
Perservative Stabilisers
0.09% Sodium Azide (NaN3)
Immunogen
Purified human C-Reactive Protein
Buffer Solution
Antiserum Preparation
Antisera to Human C-Reactive Protein were raised by repeated immunisation of goats with highly purified antigen
Target Species
Human
Preparation and Storage
Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.
Other Notes
Small volumes of anti-CRP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-CRP antibody
MBS224050 recognizes human C-reactive protein (CRP), a calcium-binding acute phase reactant belonging to the pentraxin family which is secreted into the plasma by the liver, in response to cytokine stimulation. Levels of plasma CRP are significantly increased during the acute phase response, tissue injury and infection and can be used diagnostically as a marker of inflammation, disease progress and risk assessment of cardiovascular disease (CVD). This reagent is available in bulk quantities and may be made available in other formats. Please enquire for further details.
Applications Tested/Suitable for anti-CRP antibody
Turbidimetry (TB)
NCBI/Uniprot data below describe general gene information for CRP. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
10,415 Da[Similar Products]
NCBI Official Full Name
C-reactive protein
NCBI Official Synonym Full Names
C-reactive protein, pentraxin-related
NCBI Official Symbol
NCBI Official Synonym Symbols
NCBI Protein Information
C-reactive protein; pentraxin 1
UniProt Protein Name
C-reactive protein
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
UniProt Entry Name
CRP_HUMAN
NCBI Summary for CRP
The protein encoded by this gene belongs to the pentaxin family. It is involved in several host defense related functions based on its ability to recognize foreign pathogens and damaged cells of the host and to initiate their elimination by interacting with humoral and cellular effector systems in the blood. Consequently, the level of this protein in plasma increases greatly during acute phase response to tissue injury, infection, or other inflammatory stimuli. [provided by RefSeq, Sep 2009]
UniProt Comments for CRP
CRP: Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. Belongs to the pentaxin family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 1q23.2

Cellular Component: extracellular space; growth cone; extracellular region; filopodium

Molecular Function: choline binding; protein binding; protein homodimerization activity; low-density lipoprotein receptor binding; complement component C1q binding; virion binding; low-density lipoprotein binding; cholesterol binding; calcium ion binding

Biological Process: protein polymerization; defense response to Gram-positive bacterium; response to ethanol; wound healing; negative regulation of vasodilation; positive regulation of superoxide release; response to lead ion; acute-phase response; response to hypoxia; opsonization; inflammatory response; complement activation, classical pathway; aging
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Organs/Tissues associated with anti-CRP antibody
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