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anti-CD70 antibody :: Chicken CD70 Polyclonal Antibody

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Catalog # MBS588267
Unit / Price
  0.1 mg  /  $625 +1 FREE 8GB USB
Immunohistochemistry (IHC)
Product Name

CD70, Polyclonal Antibody

Also Known As

CD70 Antigen Chicken Polyclonal Antibody

Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
193
3D Structure
ModBase 3D Structure for P32970
Clonality
Polyclonal
Host
Chicken
Form/Format
Lyophilized purified total IgY in PBS pH7.4
Preservative
Ampicillin and streptomycin, 0.05% sodium aside.
Preparation and Storage
Lyophilized antibody can be kept at 4 degree C for up to 3 months and should be kept at-20 degree C for long-term storage.
To avoid freeze-thaw cycles, reconstituted antibody should be aliquoted before freezing for short-term storage (-20 degree C) or for long-term storage (-80 degree C).
For maximum recovery of product centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.
Other Notes
Small volumes of anti-CD70 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Immunohistochemistry (IHC) of anti-CD70 antibody
Paraffin embedded pig coronary artery tissue sections were stained for CD70 presence with the anti-chicken IgY and the reaction was visualized with anti-chicken antibody (red). DNA was stained with DAPI (blue) and the smooth muscle layer with rabbit anti-smooth muscle actin (green). CD70 shows significant staining in the endothelial cell layer and the adventitia.
anti-CD70 antibody Immunohistochemistry (IHC) (IHC) image
NCBI/Uniprot data below describe general gene information for CD70. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
23,438 Da
NCBI Official Full Name
CD70 antigen isoform 1
NCBI Official Synonym Full Names
CD70 molecule
NCBI Official Symbol
NCBI Official Synonym Symbols
CD27L; CD27-L; CD27LG; TNFSF7; TNLG8A
  [Similar Products]
NCBI Protein Information
CD70 antigen
UniProt Protein Name
CD70 antigen
UniProt Synonym Protein Names
CD27 ligand; CD27-L; Tumor necrosis factor ligand superfamily member 7; CD_antigen: CD70
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
CD27L; CD27LG; TNFSF7; CD27-L  [Similar Products]
NCBI Summary for CD70
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis. [provided by RefSeq, Jul 2008]
UniProt Comments for CD70
Cytokine that binds to CD27. Plays a role in T-cell activation. Induces the proliferation of costimulated T-cells and enhances the generation of cytolytic T-cells.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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