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anti-RAD30 antibody :: Rabbit DNA polymerase eta Polyclonal Antibody

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Catalog # MBS540111
Unit / Price
  0.1 mg Affinity-Purified  /  $390 +1 FREE 8GB USB
anti-RAD30 antibody
Product Name

DNA polymerase eta (RAD30), Polyclonal Antibody

Popular Item
Full Product Name

DNA polymerase eta Antibody Affinity Purified

Product Synonym Names
DNA polymerase eta; FLJ16395; FLJ21978; POLH; polymerase DNA directed eta; RAD30; RAD30 homolog A; Xeroderma pigmentosum variant type protein; XPV antibody
Matching Pairs
Antibody/Peptide Pairs
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q04049
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Saccharomyces cerevisae
Form/Format
Affinity Purified
Concentration
0.70-0.98 ug/ul in antibody stabilization buffer (lot specific)
Immunogen
Synthetic peptide taken within amino acid region 200-300 on Chain A, Yeast DNA polymerase Eta.
Expression
Induced by UV radiation and heat shock. The mRNA is stabilized during stationary phase.
Molecular Function
Damaged DNA binding, Metal ion binding, DNA-directed DNA polymerase activity
Structure
Interacts with POL30. This interaction is essential for the polymerase eta function.
Subcellular Location
Nucleus
Preparation and Storage
-20 degree C for long term storage
Other Notes
Small volumes of anti-RAD30 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-RAD30 antibody
Affinity Purified Chain B, Yeast DNA polymerase Eta Antibody
DNA polymerase specifically involved in DNA repair. Plays an important role in translesion synthesis, where the normal high fidelity DNA polymerases cannot proceed and DNA synthesis stalls. Plays an important role in the repair of UV-induced pyrimidine dimers. Depending on the context, it inserts the correct base, but causes frequent base transitions and transversions. Efficiently incorporates nucleotides opposite to other UV or oxidative DNA damages like O(6)-methylguanine, 7, 8-dihydro-8-oxoguanine, 2, 6-diamino-4-hydroxy-5-formamidopyrimidine of 2'-deoxyguanosine (FaPydG), or p-benzoquinone DNA adducts.
Applications Tested/Suitable for anti-RAD30 antibody
ELISA (EIA), Western Blot (WB)
Application Notes for anti-RAD30 antibody
Dot Blot: 1:10,000
ELISA: 1:10,000
Western Blot: 1:500
NCBI/Uniprot data below describe general gene information for RAD30. It may not necessarily be applicable to this product.
NCBI GI #
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
Molecular Weight
71,515 Da[Similar Products]
NCBI Official Full Name
Chain A, Yeast Dna Polymerase Eta
UniProt Protein Name
DNA polymerase eta
UniProt Synonym Protein Names
Radiation-sensitive protein 30
Protein Family
UniProt Gene Name
RAD30  [Similar Products]
UniProt Synonym Gene Names
UniProt Entry Name
POLH_YEAST
UniProt Comments for RAD30
DNA polymerase specifically involved in DNA repair. Plays an important role in translesion synthesis, where the normal high fidelity DNA polymerases cannot proceed and DNA synthesis stalls. Plays an important role in the repair of UV-induced pyrimidine dimers. Depending on the context, it inserts the correct base, but causes frequent base transitions and transversions. Efficiently incorporates nucleotides opposite to other UV or oxidative DNA damages like O(6)-methylguanine, 7,8-dihydro-8-oxoguanine, 2,6-diamino-4-hydroxy-5-formamidopyrimidine of 2'-deoxyguanosine (FaPydG), or p-benzoquinone DNA adducts.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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