NP_714913.1
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
34,961 Da
NCBI Official Full Name
ELMO domain-containing protein 2
NCBI Official Synonym Full Names
ELMO/CED-12 domain containing 2
NCBI Protein Information
ELMO domain-containing protein 2
UniProt Protein Name
ELMO domain-containing protein 2
UniProt Entry Name
ELMD2_HUMAN
NCBI Summary for ELMOD2
This gene encodes one of six engulfment and motility (ELMO) domain-containing proteins. This gene is thought to play a role in antiviral responses. Mutations in this gene may be involved in the cause of familial idiopathic pulmonary fibrosis. [provided by RefSeq, Sep 2010]
UniProt Comments for ELMOD2
ELMOD2: Acts as a GTPase-activating protein (GAP) toward guanine nucleotide exchange factors like ARL2, ARL3, ARF1 and ARF6, but not for GTPases outside the Arf family. Regulates IFN-related antiviral responses.
Chromosomal Location of Human Ortholog: 4q31.1
Cellular Component: cytoskeleton; membrane
Molecular Function: GTPase activator activity
Biological Process: regulation of defense response to virus; defense response to virus; phagocytosis; positive regulation of GTPase activity
Disease: Pulmonary Fibrosis, Idiopathic
Research Articles on ELMOD2
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Diseases associated with anti-ELMOD2 antibody
Organs/Tissues associated with anti-ELMOD2 antibody
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