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anti-EGF antibody :: Chicken Epidermal Growth Factor (EGF) Polyclonal Antibody

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Catalog # MBS588214
Unit / Price
  0.1 mg  /  $625 +1 FREE 8GB USB
Immunohistochemistry (IHC)
Product Name

Epidermal Growth Factor (EGF), Polyclonal Antibody

Popular Item
Also Known As

Epidermal Growth Factor (EGF) Chicken Polyclonal Antibody

Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
1207
Clonality
Polyclonal
Host
Chicken
Form/Format
Lyophilized purified total IgY in PBS pH7.4
Preservative
Ampicillin and streptomycin, 0.05% sodium aside.
Preparation and Storage
Lyophilized antibody can be kept at 4 degree C for up to 3 months and should be kept at-20 degree C for long-term storage.
To avoid freeze-thaw cycles, reconstituted antibody should be aliquoted before freezing for short-term storage (-20 degree C) or for long-term storage (-80 degree C).
For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.
Other Notes
Small volumes of anti-EGF antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Immunohistochemistry (IHC) of anti-EGF antibody
Paraffin embedded pig coronary artery tissue section was stained for EGF presence with the anti-chicken IgY and the reaction was visualized with anti-chicken antibody (red). DNA was stained with DAPI (blue) and the smooth muscle layer with rabbit ant-smooth muscle actin (green) EGF shows signihcant staining in the endothelial cell layer and the adventitia
anti-EGF antibody Immunohistochemistry (IHC) (IHC) image
NCBI/Uniprot data below describe general gene information for EGF. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
129,256 Da
NCBI Official Full Name
epidermal growth factor (beta-urogastrone)
NCBI Official Synonym Full Names
epidermal growth factor
NCBI Official Symbol
NCBI Official Synonym Symbols
URG; HOMG4
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NCBI Protein Information
pro-epidermal growth factor
UniProt Protein Name
Pro-epidermal growth factor
UniProt Synonym Protein Names
Epidermal growth factorAlternative name(s):Urogastrone
UniProt Gene Name
UniProt Synonym Gene Names
NCBI Summary for EGF
This gene encodes a member of the epidermal growth factor superfamily. The encoded preproprotein is proteolytically processed to generate the 53-amino acid epidermal growth factor peptide. This protein acts a potent mitogenic factor that plays an important role in the growth, proliferation and differentiation of numerous cell types. This protein acts by binding with high affinity to the cell surface receptor, epidermal growth factor receptor. Defects in this gene are the cause of hypomagnesemia type 4. Dysregulation of this gene has been associated with the growth and progression of certain cancers. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. [provided by RefSeq, Jan 2016]
UniProt Comments for EGF
EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. Can induce neurite outgrowth in motoneurons of the pond snail Lymnaea stagnalis in vitro (PubMed:10964941).
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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