NP_000151.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
glucagon receptor
NCBI Official Synonym Full Names
glucagon receptor
NCBI Official Synonym Symbols
NCBI Protein Information
glucagon receptor
UniProt Protein Name
Glucagon receptor
UniProt Synonym Gene Names
NCBI Summary for GCGR
The protein encoded by this gene is a glucagon receptor that is important in controlling blood glucose levels. Defects in this gene are a cause of non-insulin-dependent diabetes mellitus (NIDDM).[provided by RefSeq, Jan 2010]
UniProt Comments for GCGR
G-protein coupled receptor for glucagon that plays a central role in the regulation of blood glucose levels and glucose homeostasis. Regulates the rate of hepatic glucose production by promoting glycogen hydrolysis and gluconeogenesis. Plays an important role in mediating the responses to fasting. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Promotes activation of adenylate cyclase. Besides, plays a role in signaling via a phosphatidylinositol-calcium second messenger system.
Research Articles on GCGR
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Products associated with anti-GCGR antibody
Pathways associated with anti-GCGR antibody
Diseases associated with anti-GCGR antibody
Organs/Tissues associated with anti-GCGR antibody
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