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anti-LXRb antibody :: Rabbit Liver X Receptor Beta Polyclonal Antibody

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Catalog # MBS2033736 (SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment)
Unit / Price
  0.01 mg  /  $110 +1 FREE 8GB USB
  0.02 mg  /  $130 +1 FREE 8GB USB
  0.05 mg  /  $185 +1 FREE 8GB USB
  0.1 mg  /  $230 +1 FREE 8GB USB
  0.2 mg  /  $345 +1 FREE 8GB USB
  1 mg  /  $825 +1 FREE 8GB USB
Product Name

Liver X Receptor Beta (LXRb), Polyclonal Antibody

Popular Item
Full Product Name

Polyclonal Antibody to Liver X Receptor Beta (LXRb)

Product Synonym Names
NR1-H2; UNR; LXR-B; NER; NER-I; RIP15; Nuclear Receptor Subfamily 1,Group H,Member 2; Ubiquitously-Expressed Nuclear Receptor; Oxysterols receptor LXR-beta
Matching Pairs
Matching Pairs
Unconjugated Antibody: Liver X Receptor Beta (MBS2033736)
APC-CY7 Conjugated Antibody: Liver X Receptor Beta (LXRb) (MBS2070177)
Matching Pairs
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
MBS2033736 Technical Datasheet
3D Structure
ModBase 3D Structure for Q60644
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Supplied as solution form in 0.01M PBS, pH7.4, containing 0.05% Proclin-300,50% glycerol.
0.47mg/ml (lot specific)
Organism Species
Mus musculus(Mouse)
Polyclonal antibody preparation
Recombinant LXRb (Met1~Glu446) expressed in E.coli
Conjugated Antibody
The APC-Cy7 conjugated antibody version of this item is also available as catalog #MBS2070177
Preparation and Storage
Storage: Avoid repeated freeze/thaw cycles.
Store at 4ºC for frequent use.
Aliquot and store at -20ºC for 12 months.

Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
ISO Certification
Manufactured in an ISO 9001:2008 and ISO 13485:2003 Certified Laboratory.
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Other Notes
Small volumes of anti-LXRb antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-LXRb antibody
Application Notes for anti-LXRb antibody
Western blotting: 0.5-2)Ug/mL;1:230-900
Immunohistochemistry: 5-20) Ug/mL;1:23-90
Immunocytochemistry: 5-20)Ug/mL;1:23-90

Optimal working dilutions must be determined by end user.

Western Blot (WB) of anti-LXRb antibody
Western Blot: Sample: Mouse Liver lysate; Primary Ab: 1ug/ml Rabbit Anti-Mouse LXRb Antibody Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody
anti-LXRb antibody Western Blot (WB) (WB) image
Western Blot (WB) of anti-LXRb antibody
Western Blot: Sample: Recombinant protein.
anti-LXRb antibody Western Blot (WB) (WB) image
Immunohistochemistry (IHC) of anti-LXRb antibody
DAB staining on fromalin fixed paraffin- embedded liver tissue)
anti-LXRb antibody Immunohistochemistry (IHC) (IHC) image
NCBI/Uniprot data below describe general gene information for LXRb. It may not necessarily be applicable to this product.
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Related Accession #
NCBI Official Full Name
oxysterols receptor LXR-beta isoform a
NCBI Official Synonym Full Names
nuclear receptor subfamily 1, group H, member 2
NCBI Official Symbol
Nr1h2  [Similar Products]
NCBI Official Synonym Symbols
UR; LXR; Unr; LXRB; NER1; OR-1; Unr2; RIP15; LXRBSV; LXRbeta; AI194859
  [Similar Products]
NCBI Protein Information
oxysterols receptor LXR-beta
UniProt Protein Name
Oxysterols receptor LXR-beta
UniProt Synonym Protein Names
Liver X receptor beta; Nuclear receptor subfamily 1 group H member 2; Retinoid X receptor-interacting protein No.15; Ubiquitously-expressed nuclear receptor
UniProt Gene Name
Nr1h2  [Similar Products]
UniProt Synonym Gene Names
Lxrb; Rip15; Unr; Unr2  [Similar Products]
UniProt Comments for LXRb
LXR-beta: Orphan receptor. Binds preferentially to double-stranded oligonucleotide direct repeats having the consensus half-site sequence 5'-AGGTCA-3' and 4-nt spacing (DR-4). Regulates cholesterol uptake through MYLIP-dependent ubiquitination of LDLR, VLDLR and LRP8. Forms a heterodimer with RXR. Ubiquitous. Belongs to the nuclear hormone receptor family. NR1 subfamily.

Protein type: Nuclear receptor

Chromosomal Location of Human Ortholog: 7|7 B3

Cellular Component: cytoplasm; nucleus

Molecular Function: apolipoprotein A-I receptor binding; ATPase binding; DNA binding; DNA binding transcription factor activity; ligand-dependent nuclear receptor activity; metal ion binding; protein binding; retinoid X receptor binding; sequence-specific DNA binding; steroid hormone receptor activity; zinc ion binding

Biological Process: cellular lipid metabolic process; cholesterol homeostasis; lipid homeostasis; negative regulation of cholesterol storage; negative regulation of gene expression; negative regulation of lipid transport; negative regulation of pinocytosis; negative regulation of proteolysis; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; positive regulation of cellular protein metabolic process; positive regulation of cholesterol efflux; positive regulation of cholesterol transport; positive regulation of fatty acid biosynthetic process; positive regulation of gene expression; positive regulation of high-density lipoprotein particle assembly; positive regulation of lipid storage; positive regulation of lipoprotein lipase activity; positive regulation of pancreatic juice secretion; positive regulation of secretion of lysosomal enzymes; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-templated; positive regulation of triglyceride biosynthetic process; regulation of cholesterol homeostasis; regulation of transcription from RNA polymerase II promoter; regulation of transcription, DNA-templated; retinoic acid receptor signaling pathway; steroid hormone mediated signaling; transcription, DNA-dependent
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While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

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