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anti-N antibody :: Rabbit anti-Lassa virus N Polyclonal Antibody

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Catalog # MBS7052613
Unit / Price
  0.1 mg  /  $165 +1 FREE 8GB USB
anti-N antibody
Product Name

N, Polyclonal Antibody

Popular Item
Also Known As

N Antibody

Product Synonym Names
Nucleoprotein; Nucleocapsid protein; Protein N; N
Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
MBS7052613 Technical Datasheet
Immunogen Sequence Length
569
3D Structure
ModBase 3D Structure for P13699
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Lassa virus
Purity/Purification
>95%, Protein G purified
Form/Format
Liquid
Immunogen
Recombinant Lassa virus Nucleoprotein (1-569AA)
Conjugation
Non-conjugated
Preservative
0.03% Proclin 300
Constituents
50% Glycerol, 0.01M PBS, pH 7.4
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-N antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-N antibody
Encapsidates the genome, protecting it from nucleases. The encapsidated genomic RNA is termed the nucleocapsid (NC). Serves as template for viral transcription and replication. The increased presence of protein N in host cell does not seem to trigger the switch from transcription to replication as observed in other negative strain RNA viruses. Disables the host innate defense by interfering with beta interferon (IFNB) production through the inhibition of host IRF3 phosphorylation and activation by host IKBKE. Through the interaction with host IKBKE, strongly inhibits the phosphorylation and nuclear translocation of IRF3, a protein involved in IFN activation pathway, leading to the inhibition of IFNB and IRF3-dependent promoters activation (By similarity).
Applications Tested/Suitable for anti-N antibody
ELISA (EIA)
NCBI/Uniprot data below describe general gene information for N. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
Molecular Weight
62,998 Da
NCBI Official Full Name
nucleoprotein
NCBI Official Symbol
LASVsSgp1  [Similar Products]
NCBI Protein Information
nucleoprotein
UniProt Protein Name
Nucleoprotein
UniProt Synonym Protein Names
Nucleocapsid protein; Protein N
Protein Family
UniProt Gene Name
UniProt Comments for N
Encapsidates the genome, protecting it from nucleases. The encapsidated genomic RNA is termed the nucleocapsid (NC). Serves as template for viral transcription and replication. The increased presence of protein N in host cell does not seem to trigger the switch from transcription to replication as observed in other negative strain RNA viruses. Disables the host innate defense by interfering with beta interferon (IFNB) production through the inhibition of host IRF3 phosphorylation and activation by host IKBKE. Through the interaction with host IKBKE, strongly inhibits the phosphorylation and nuclear translocation of IRF3, a protein involved in IFN activation pathway, leading to the inhibition of IFNB and IRF3-dependent promoters activation ().
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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