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anti-TAC3 antibody :: Rabbit NEUROKININ B Polyclonal Antibody

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Catalog # MBS222688
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anti-TAC3 antibody
Product Name

NEUROKININ B (TAC3), Polyclonal Antibody

Full Product Name

RABBIT ANTI HUMAN NEUROKININ B

Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
162330
3D Structure
ModBase 3D Structure for Q9UHF0
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Specificity
This item is specific for human neurokinin B.
Form/Format
Purified
Ig fraction - lyophilised
Reconstitution
Reconstitute with 50 ul of sterile distilled water. For long term storage the addition of a preservative is recommended.
Preparation
Immunogen
Synthetic human neurokinin B conjugated to thyroglobulin by the carbodiimide method
Buffer Solution
Target Species
Human
Preparation and Storage
Store at -20 degree C only. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 12 months from date of reconstitution.
Other Notes
Small volumes of anti-TAC3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-TAC3 antibody
MBS222688 is specific for human neurokinin B.
Applications Tested/Suitable for anti-TAC3 antibody
Western Blot (WB)
NCBI/Uniprot data below describe general gene information for TAC3. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
11,358 Da[Similar Products]
NCBI Official Full Name
tachykinin-3 isoform 2 preproprotein
NCBI Official Synonym Full Names
tachykinin 3
NCBI Official Symbol
NCBI Official Synonym Symbols
NKB; HH10; NKNB; PRO1155; ZNEUROK1
  [Similar Products]
NCBI Protein Information
tachykinin-3; gamma tachykinin 3; neurokinin b; neuromedin K; preprotachykinin B; preprotachykinin-B
UniProt Protein Name
Tachykinin-3
UniProt Synonym Protein Names
ZNEUROK1Neurokinin-B; NKBAlternative name(s):Neuromedin-K
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
NKNB; NKB  [Similar Products]
UniProt Entry Name
TKNK_HUMAN
NCBI Summary for TAC3
This gene encodes a member of the tachykinin family of secreted neuropeptides. The encoded protein is primarily expressed in the central and peripheral nervous system and functions as a neurotransmitter. This protein is the ligand for the neurokinin-3 receptor. This protein is also expressed in the outer syncytiotrophoblast of the placenta and may be associated with pregnancy-induced hypertension and pre-eclampsia. Mutations in this gene are associated with normosmic hypogonadotropic hypogonadism. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2010]
UniProt Comments for TAC3
TAC3: Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles. Belongs to the tachykinin family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 12q13.3

Cellular Component: extracellular space; extracellular region

Molecular Function: protein binding; receptor binding

Biological Process: tachykinin signaling pathway; neuropeptide signaling pathway; female pregnancy

Disease: Hypogonadotropic Hypogonadism 10 With Or Without Anosmia
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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