• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

Rabbit p35, Baculovirus Polyclonal Antibody

Scan QR to view Datasheet
Catalog # MBS6006015
Unit / Price
Scan QR to view Datasheet
  0.05 mL  /  $500 +1 FREE 8GB USB
anti-p35, Baculovirus antibody
Product Name

p35, Baculovirus, Polyclonal Antibody

Popular Item
Full Product Name

p35, Baculovirus

Product Synonym Names
Anti -p35, Baculovirus
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Specificity
Recognizes p35 baculovirus.
Purity/Purification
Grade: Serum
Purity: Serum
Form/Format
Supplied as a liquid, 0.05% sodium azide.
Immunogen
Recombinant corresponding to full-length p35 baculovirus protein.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Other Notes
Small volumes of anti-p35, Baculovirus antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-p35, Baculovirus antibody
The baculoviruses are a large, diverse family of DNA viruses that have evolved a number of mechanisms to manipulate thier insect hosts. One of these is the ability to regulate apoptosis during infection by expressing proteins that can inhibit caspase activation, including the caspase inhibitor p35 and the inhibitor of apoptosis (IAP) proteins. The p35 baculovirus protein strongly inhibits caspase enzymatic activity, and is the the most broadly acting caspase inhibitor protein known. p35 baculovirus forms essentially irreversible complexes with its target caspases in a process that is accompanied by the cleavage of p35, generating two fragments of approximately 10kD and 25kD. These cleavage fragments remain associated with caspases and thereby block caspase activity. The ability of p35 to inhibit caspases along with the central role of caspases in the apoptotic process enables p35 baculovirus to block apoptosis in a phylogentically broad range of cells, and in response to a wide variety of apoptotic induction signals. For example, over expression of p35 in mammalian, insect, and nematode cells results in resistance to apoptosis.
Applications Tested/Suitable for anti-p35, Baculovirus antibody
Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC)
Application Notes for anti-p35, Baculovirus antibody
Suitable for use in Western Blot, Immunohistochemistry and Immunoprecipitation.
Dilution: Western Blot: 1:1000-1:2000. p35 baculovirus may be observed as one or multiple bands. p35 baculovirus is cleaved during reaction with caspases. 10 and 25kD fragments have been described (3,4).
Immunohistochemistry (FFPE): 1:1000-1:5000
Immunohistochemistry: Frozen sections
Immunoprecipitation: 1:50-1:200
NCBI/Uniprot data below describe general gene information for p35, Baculovirus. It may not necessarily be applicable to this product.
NCBI GI #
NCBI Accession #
NCBI Official Full Name
P35
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000