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anti-PR3 antibody :: Rabbit Proteinase 3 (PR3) Polyclonal Antibody

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Catalog # MBS2005777 (SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment)
Unit / Price
Scan QR to view Datasheet
  0.01 mg  /  $110 +1 FREE 8GB USB
  0.02 mg  /  $125 +1 FREE 8GB USB
  0.05 mg  /  $175 +1 FREE 8GB USB
  0.1 mg  /  $225 +1 FREE 8GB USB
  0.2 mg  /  $330 +1 FREE 8GB USB
  1 mg  /  $785 +1 FREE 8GB USB
Product Name

Proteinase 3 (PR3), Polyclonal Antibody

Popular Item
Full Product Name

Polyclonal Antibody to Proteinase 3 (PR3)

Product Gene Name
Matching Pairs
Unconjugated Antibody: Proteinase 3 (PR3) (MBS2005777)
Biotin Conjugated Antibody: Proteinase 3 (PR3) (MBS2004812)
Matching Pairs
Matching Pairs
Unconjugated Antibody: Proteinase 3 (PR3) (MBS2005777)
APC-CY7 Conjugated Antibody: Proteinase 3 (PR3) (MBS2055151)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
MBS2005777 Technical Datasheet
3D Structure
ModBase 3D Structure for Q61096
Clonality
Polyclonal
Host
Rabbit
Purity/Purification
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Form/Format
Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Concentration
1 mg/ml (lot specific)
Immunogen
Recombinant PR3 (Ala24~Leu249) expressed in E.coli.
Conjugated Antibody
The APC conjugated antibody version of this item is also available as catalog #MBS2055153
Preparation and Storage
Storage: Avoid repeated freeze/thaw cycles.
Store at 4ºC for frequent use.
Aliquot and store at -20ºC for 12 months.

Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
ISO Certification
Manufactured in an ISO 9001:2008 and ISO 13485:2003 Certified Laboratory.
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Other Notes
Small volumes of anti-PR3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-PR3 antibody
WB; IHC; ICC; IP.
Application Notes for anti-PR3 antibody
Western blotting: 0.5-2 ug/mL;1:500-2000
Immunohistochemistry: 5-20 ug/mL;1:50-200
Immunocytochemistry: 5-20 ug/mL;1:50-200

Optimal working dilutions must be determined by end user.

Western Blot (WB) of anti-PR3 antibody
Western Blot: Sample. Lane1: Mouse Lung Tissue; Lane2: Mouse Spleen Tissue.
anti-PR3 antibody Western Blot (WB) (WB) image
Western Blot (WB) of anti-PR3 antibody
Western Blot: Sample: Recombinant protein.
anti-PR3 antibody Western Blot (WB) (WB) image
Immunohistochemistry (IHC) of anti-PR3 antibody
DAB staining on IHC-P. Samples: Mouse Tissue)
anti-PR3 antibody Immunohistochemistry (IHC) (IHC) image
NCBI/Uniprot data below describe general gene information for PR3. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
myeloblastin
NCBI Official Synonym Full Names
proteinase 3
NCBI Official Symbol
Prtn3  [Similar Products]
NCBI Official Synonym Symbols
PR3; mPR3
  [Similar Products]
NCBI Protein Information
myeloblastin
UniProt Protein Name
Myeloblastin
UniProt Synonym Protein Names
Proteinase 3; PR-3
UniProt Gene Name
Prtn3  [Similar Products]
UniProt Synonym Gene Names
UniProt Comments for PR3
PRTN3: Polymorphonuclear leukocyte serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro) and causes emphysema when administered by tracheal insufflation to hamsters. Belongs to the peptidase S1 family. Elastase subfamily.

Protein type: Cell cycle regulation; EC 3.4.21.76; Protease

Chromosomal Location of Human Ortholog: 10 C1|10 39.72 cM

Cellular Component: cytosol; extracellular matrix; extracellular space; plasma membrane

Molecular Function: enzyme binding; hydrolase activity; peptidase activity; protein binding; serine-type endopeptidase activity; serine-type peptidase activity

Biological Process: collagen catabolic process; negative regulation of phagocytosis; phagocytosis; proteolysis
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Products associated with anti-PR3 antibody
 Reference Product  PubMed Publications
 Myb antibody  >2 publications with PR3 and Myb
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