• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

anti-sanA antibody :: Rabbit Vancomycin Polyclonal Antibody

Scan QR to view Datasheet
Catalog # MBS623181
Unit / Price
Scan QR to view Datasheet
  0.1 mL  /  $320 +1 FREE 8GB USB
  0.2 mL  /  $460 +1 FREE 8GB USB
anti-sanA antibody
Product Name

Vancomycin (sanA), Polyclonal Antibody

Popular Item
Full Product Name

Vancomycin

Product Synonym Names
Anti -Vancomycin
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Chromosome Location
NC_000913.2 (2230900..2231619)
3D Structure
ModBase 3D Structure for P0AFY2
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Specificity
Recognizes Vancomycin: 100%.
Purity/Purification
Affinity Purified
Purified by Protein G affinity chromatography
Form/Format
Supplied as a liquid in PBS, pH 7.4, 0.1% sodium azide.
Immunogen
Vancomycin conjugated to KLH
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Other Notes
Small volumes of anti-sanA antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-sanA antibody
Vancomycin is an aminoglycoside antibiotic, used in the treatment of infections caused by Gram-positive bacteria. vancomycin is not active against Gram-negative bacteria (except some non-gonococcal species of Neisseria). The main target of this antibiotic is the D-alanyl-D-alanine terminal dipeptide of peptidoglycan precursors, used by bacteria for constructing their cell walls. This prevents the reaction used to link peptidoglycan precursors together from taking place. Vancomycin binds with the substrate, not the enzyme, in contrast to the way penicillin inhibits peptidoglycan synthesis.

The large hydrophilic molecule is able to form hydrogen bond interactions with the terminal D-alanyl-D-alanine moieties of the NAM/NAG-peptides. Under normal circumstances, this is a five-point interaction. This binding of vancomycin to the D-Ala-D-Ala prevents cell wall synthesis in two ways. It prevents the synthesis of the long polymers of N-acetylmuramic acid (NAM) and N-acetylglucosamine (NAG) that form the backbone strands of the bacterial cell wall, and it prevents the backbone polymers that do manage to form from cross-linking with each other.
Product Categories/Family for anti-sanA antibody
Applications Tested/Suitable for anti-sanA antibody
ELISA (EL/EIA)
Application Notes for anti-sanA antibody
Suitable for use in Indirect ELISA.
NCBI/Uniprot data below describe general gene information for sanA. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
Molecular Weight
27,287 Da[Similar Products]
NCBI Official Full Name
vancomycin high temperature exclusion protein; mutants have a defective envelope more permeable to vancomycin at 42 degrees
NCBI Official Symbol
NCBI Official Synonym Symbols
ECK2137; JW2132; sfiX; yeiF
  [Similar Products]
NCBI Protein Information
vancomycin high temperature exclusion protein; mutants have a defective envelope more permeable to vancomycin at 42 degrees
UniProt Protein Name
Protein SanA
UniProt Gene Name
UniProt Synonym Gene Names
UniProt Entry Name
SANA_ECOLI
NCBI Summary for sanA
ydcF and ycbC (COG1434) and sanA and yjgQ (COG2949) are four members of the DUF218 superfamily (PF02698). [More information is available at EcoGene: EG12025]. sanA encodes an inner membrane protein which is likely to be involved in cell envelope barrier functions. [More information is available at EcoCyc: EG12025].
UniProt Comments for sanA
Function: Participates in the barrier function of the cell envelope.

Subcellular location: Cell inner membrane; Single-pass membrane protein.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Products associated withanti-sanA antibody
 Reference Product  PubMed Publications
 cdd antibody  >1 publications with sanA and cdd
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000